Results 131 to 140 of about 325,490 (342)

A Machine Learning Strategy to Identity Exonic Splice Enhancers in Human Protein-coding Sequence [PDF]

open access: yesarXiv, 2004
Background: Exonic splice enhancers are sequences embedded within exons which promote and regulate the splicing of the transcript in which they are located. A class of exonic splice enhancers are the SR proteins, which are thought to mediate interactions between splicing factors bound to the 5' and 3' splice sites.
arxiv  

Splicing of SV40 late mRNA is a post-transcriptional process [PDF]

open access: bronze, 1978
Mia Horowitz   +3 more
openalex   +1 more source

Fiber Bragg Gratings with Micro‐Engineered Temperature Coefficients

open access: yesAdvanced Optical Materials, Volume 13, Issue 8, March 13, 2025.
Fiber Bragg gratings (FBGs) are intrinsically responsive to temperature and strain simultaneously. In this research, low‐loss FBGs with micro‐engineered temperature coefficients are fabricated, utilizing refractive index liquid‐filled microchannels in the cladding.
Zipei Song   +8 more
wiley   +1 more source

Improving spliced alignment by modeling splice sites with deep learning [PDF]

open access: yesarXiv
Motivation: Spliced alignment refers to the alignment of messenger RNA (mRNA) or protein sequences to eukaryotic genomes. It plays a critical role in gene annotation and the study of gene functions. Accurate spliced alignment demands sophisticated modeling of splice sites, but current aligners use simple models, which may affect their accuracy given ...
arxiv  

Optical Chaos Generation and Applications

open access: yesAdvanced Photonics Research, EarlyView.
This review comprehensively examines optical chaos generation via feedback, injection, and optoelectronic methods, emphasizing bandwidth enhancement and time‐delay suppression. Applications include chaos‐synchronized secure communication, physical random number generation, chaotic lidar for cm‐level detection, distributed fiber sensing, and terahertz ...
Wenhui Chen   +8 more
wiley   +1 more source

Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model

open access: yesAdvanced Therapeutics, Volume 8, Issue 6, June 2025.
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika   +7 more
wiley   +1 more source

In vitro RNA-RNA splicing in adenovirus 2 mRNA formation. [PDF]

open access: green, 1978
J. M. Blanchard   +3 more
openalex   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

open access: yesAdvanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han   +9 more
wiley   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

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