Results 131 to 140 of about 325,490 (342)
A Machine Learning Strategy to Identity Exonic Splice Enhancers in Human Protein-coding Sequence [PDF]
Background: Exonic splice enhancers are sequences embedded within exons which promote and regulate the splicing of the transcript in which they are located. A class of exonic splice enhancers are the SR proteins, which are thought to mediate interactions between splicing factors bound to the 5' and 3' splice sites.
arxiv
Splicing of SV40 late mRNA is a post-transcriptional process [PDF]
Mia Horowitz+3 more
openalex +1 more source
Fiber Bragg Gratings with Micro‐Engineered Temperature Coefficients
Fiber Bragg gratings (FBGs) are intrinsically responsive to temperature and strain simultaneously. In this research, low‐loss FBGs with micro‐engineered temperature coefficients are fabricated, utilizing refractive index liquid‐filled microchannels in the cladding.
Zipei Song+8 more
wiley +1 more source
Improving spliced alignment by modeling splice sites with deep learning [PDF]
Motivation: Spliced alignment refers to the alignment of messenger RNA (mRNA) or protein sequences to eukaryotic genomes. It plays a critical role in gene annotation and the study of gene functions. Accurate spliced alignment demands sophisticated modeling of splice sites, but current aligners use simple models, which may affect their accuracy given ...
arxiv
BKV splice sequences based on analysis of preferred donor and acceptor sites [PDF]
I. Seif, George Khoury, Ravi Dhar
openalex +1 more source
Optical Chaos Generation and Applications
This review comprehensively examines optical chaos generation via feedback, injection, and optoelectronic methods, emphasizing bandwidth enhancement and time‐delay suppression. Applications include chaos‐synchronized secure communication, physical random number generation, chaotic lidar for cm‐level detection, distributed fiber sensing, and terahertz ...
Wenhui Chen+8 more
wiley +1 more source
Mimicking Biochemical Traits with a Synthetic Lipid Nanoparticles SARS‐COV‐2 Model
A synthetic virus model developed using lipid nanoparticles, which incorporate encapsulated mRNA and nucleocapsid (N) protein along with surface‐conjugated spike (S) protein, mimics the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), allowing for the advancement of diagnostic product assessment.
Ignasia Handipta Mahardika+7 more
wiley +1 more source
In vitro RNA-RNA splicing in adenovirus 2 mRNA formation. [PDF]
J. M. Blanchard+3 more
openalex +1 more source
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang+14 more
wiley +1 more source