Results 181 to 190 of about 483,589 (358)

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Graphical Solution for Selection of Web Splice Bolts

, 1973
Jim Powers, Narendra K. Mehta
openalex   +2 more sources

Saccharomyces cerevisiae coordinates accumulation of yeast ribosomal proteins by modulating mRNA splicing, translational initiation, and protein turnover. [PDF]

, 1985
Jonathan R. Warner, Gopa Mitra, Willam F. Schwindinger, Mary Studeny, Howard M. Fried   +4 more
openalex   +1 more source

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

U-rich elements drive pervasive cryptic splicing in 3' UTR massively parallel reporter assays. [PDF]

Nat Commun
Dao K, Jungers CF, Djuranovic S, Mustoe AM.   +3 more
europepmc   +1 more source

138 kV splice for extruded dielectric cables. Final report

, 1977
Robert G. Fisher
openalex   +2 more sources

The human splicing code reveals new insights into the genetic determinants of disease

Science, 2015
H. Xiong, Babak Alipanahi, Leo J. Lee, Hannes Bretschneider, D. Merico, R. Yuen, Y. Hua, Serge Gueroussov, H. Najafabadi, T. Hughes, Q. Morris, Yoseph Barash, A. Krainer, N. Jojic, S. Scherer, B. Blencowe, B. Frey   +16 more
semanticscholar   +1 more source

Enhanced Media Optimize Bovine Myogenesis in 2D and 3D Models for Cultivated Meat Applications

Advanced Science, EarlyView.
This study uses multiomics approaches to characterize bovine myogenesis in vitro, identifying media components that enhance myogenic progenitor cell differentiation in 2D and 3D models. Notably, the enhanced conditions promoted formation of unique cell populations and contractile muscle cells expressing mature myogenic markers.
Christine L. Trautmann, Adhideb Ghosh, Ali Kerem Kalkan, Falko Noé, Ori Bar‐Nur   +4 more
wiley   +1 more source

TET dioxygenases localize at splicing speckles and promote RNA splicing. [PDF]

Nucleus
Hastert FD, Weber J, Bauer C, Zhadan A, Singh DND, Dix TC, Arnold R, Bessonov S, Soller M, Leonhardt H, Cardoso MC, Arroyo M.   +11 more
europepmc   +1 more source

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source