Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein [PDF]
James P. Trempe, B J Carter
openalex +1 more source
The study identifies a novel circular RNA derived from the TP53 gene (circTP53), which is upregulated in HNSCC and correlates with poor patient prognosis. It demonstrates that circTP53 promotes HNSCC progression by interacting with USP10, stabilizing both proteins, enhancing deubiquitination of p53, and thereby influencing tumor growth, with its ...
Yin Wang+11 more
wiley +1 more source
Determination of trunk neural crest cell fate and susceptibility to splicing perturbation by the DLC1-SF3B1-PHF5A splicing complex. [PDF]
Zheng Z+11 more
europepmc +1 more source
Functional analysis of alternatively spliced tyrosinase gene transcripts.
Günter Müller+3 more
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RNA splicing is a primary link between genetic variation and disease
Yang I. Li+7 more
semanticscholar +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source
SC35-mediated bZIP49 splicing regulates K⁺ channel AKT1 for salt stress adaptation in poplar. [PDF]
Liu X+11 more
europepmc +1 more source
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu+9 more
wiley +1 more source
Letter to editor: SRSF1-mediated alternative splicing regulates bladder cancer progression and cisplatin sensitivity through HIF1A/BNIP3/mitophagy axis. [PDF]
Zhao X, Wang X, Wu G, Wu G.
europepmc +1 more source