Results 221 to 230 of about 553,332 (236)

Regulatory paradigm of Dscam1 stochastic alternative splicing through conserved long-range RNA structures. [PDF]

Nucleic Acids Res
Dong H, Xu B, Wu L, Wang Z, Li Z, Xie J, Lv J, Yang W, Bao N, Qu H, Fu J, Yan R, Wang Y, Li L, Shi F, Huang J, Yang X, Jin Y.   +17 more
europepmc   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source

Ferroptosis: The Demise of Cells Through Phospholipid Peroxidation

Advanced Science, EarlyView.
The relative abundance of peroxidation‐resistant monounsaturated fatty acids (MUFAs) vs. peroxidation‐sensitive polyunsaturated fatty acids (PUFAs) incorporated into phospholipid (PL) is a key determinant of ferroptosis sensitivity, as the peroxidation of PL PUFA acyl chains (PUFA‐PL) disrupts membrane integrity, causing ferroptotic cell death ...
Shaojie Cui, Jin Ye
wiley   +1 more source

Interdependent Regulation of Alternative Splicing by Serine/Arginine-Rich and Heterogeneous Nuclear Ribonucleoprotein Splicing Factors. [PDF]

Genes (Basel)
Holmes ME, Hertel KJ.
europepmc   +1 more source

Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs

Advanced Science, EarlyView.
Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang, Yuanyuan Zhang, Choulin Chen, Xiaoxian Xu, Shenghua Qin, Junyan Qi, Yongzhou Bao, Huiming Li, Ruipu Chen, Weigang Zheng, Zhilong Chen, Lingzhao Fang, Yunxiang Zhao, Yuwen Liu   +13 more
wiley   +1 more source

Transcriptomic characterization of the aberrant alternative splicing in skeletal muscles of sarcopenia patients. [PDF]

Sci Rep
Li Y, Guo X, Li S, Wei X, Li T.
europepmc   +1 more source

Dysregulation of SRSF11 in Cancer: Mechanistic Insights and Biomarker Potential for Diagnosis and Therapy. [PDF]

J Cancer
Jun Y, Shanshan L, Jingwen X, Yu H, Jianlong X, Qingfeng S.   +5 more
europepmc   +1 more source

Insights into the structure and evolution of the human SAGA complex by affinity-ligand purification. [PDF]

Sci Adv
Damilot M, Schoeps T, Tora L, Schultz P, Lebeau L, Papai G, Ben-Shem A.   +6 more
europepmc   +1 more source

A novel non-sense variant in <i>GSDME</i> causing exon skipping associated with DFNA5 in a large Chinese family. [PDF]

Front Neurol
Yang B, Zhu M, Long X, Wan S, Lu Y, Yuan H, Hua Q.   +6 more
europepmc   +1 more source

Decoding SR protein regulation: kinases, phosphatases, and therapeutic targeting strategies. [PDF]

Cell Oncol (Dordr)
Liu N, van der Ende F, van de Water B, Le Dévédec SE.   +3 more
europepmc   +1 more source