Results 231 to 240 of about 396,812 (264)

A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics

Advanced Science, EarlyView.
Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang, Jun Liu, Qi Zhao, Huilong Yin, Angang Yang, Minhua Zheng, Rui Zhang   +6 more
wiley   +1 more source

mRNA processing in cancer immunotherapy: emerging targets, resistance mechanisms, and therapeutic opportunities. [PDF]

Front Immunol
Yukselten Y, Ahmad H, Shoultout M, Iqbal U, Masood F, Sutton RE.   +5 more
europepmc   +1 more source

ASPIRE: Accurate alternative splicing prediction from limited RNA sequencing data and a minimal gene set. [PDF]

PLoS Comput Biol
Eisenberg R, Rahamim E, Kopel E, Danan-Gotthold M, Levanon EY, Lindenbaum O.   +5 more
europepmc   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

Advanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu, Zhou Jiang, Lin Chen, Gowena Ling Yi Goh, Weijing Li, Qian He, Xintong Chen, Rui Li, Yuxuan Liu, Ning Li, Tao Zhou, Peng Xu   +11 more
wiley   +1 more source

Crosstalk between alternative splicing and non-coding RNAs in hepatocellular carcinoma: from regulatory mechanism to therapeutic implications. [PDF]

Noncoding RNA Res
Wang D, Zhong J, Liao Z.
europepmc   +1 more source

Silencing with precision: In silico strategies for antisense oligonucleotide engineering. [PDF]

Mol Biol Rep
Nagaraj A, Kavana CP, Harendra B, Srinivasa S, Dharmashekara C, Kollur SP, Shreevatsa B, Shivamallu C.   +7 more
europepmc   +1 more source

Arthropod‐Inspired Miniature Modular Vibration Direct‐Drive Robot With Untethered Locomotion

Advanced Science, EarlyView.
This work presents an arthropod‐inspired untethered miniature modular vibration direct‐drive robot. By utilizing standardized driving units and nested locking interfaces, on‐demand reconfiguration into quadruped, hexapod, octopod, and circular morphologies is achieved.
Shijing Zhang, Ziteng Liu, Youwei Liu, Dehong Wang, Yingxiang Liu   +4 more
wiley   +1 more source

A precise splice: proper splicing patterns required for appropriate lipid metabolism during callus induction with cytokinin. [PDF]

Plant Physiol
Kearly A.
europepmc   +1 more source

Multiple intron motifs have redundant functions in the trans-splicing of the mod(mdg4) locus. [PDF]

Nucleic Acids Res
Soldatova I, Beginyazova O, Maksimenko O, Fan YJ, Xu YZ, Shender V, Arapidi G, Georgiev P, Tikhonov M.   +8 more
europepmc   +1 more source

Splicing factor HNRNPD and alternative splicing of MAP4K4 are associated with cell apoptosis and immune microenvironment features in Wilms' tumor. [PDF]

PLoS One
Yang C, Liao M, Xu H, Wang J, Bao H, Zhang M, Li C, Zheng T, Li G.   +8 more
europepmc   +1 more source