Results 131 to 140 of about 14,445,596 (144)

RNA splicing factor RBFOX2 is a key factor in the progression of cancer and cardiomyopathy. [PDF]

Clin Transl Med
Shen J, Shentu J, Zhong C, Huang Q, Duan S.   +4 more
europepmc   +1 more source

Splicing factor SRSF1 attenuates cardiomyocytes apoptosis via regulating alternative splicing of Bcl2L12. [PDF]

Cell Biosci
Xie Y, Yang Z, Chen W, Zhong C, Li M, Zhang L, Cheng T, Deng Q, Wang H, Ju J, Du Z, Liang H.   +11 more
europepmc   +1 more source

Deletion of splicing factor Cdc5 in Toxoplasma disrupts transcriptome integrity, induces abortive bradyzoite formation, and prevents acute infection in mice. [PDF]

Nat Commun
Kashyap P, Aswale KR, Deshmukh AS.
europepmc   +1 more source

H₂S promotes flowering in <i>Brassica rapa</i> ssp. <i>pekinensis</i> by persulfidation of the splicing factor BraATO2. [PDF]

Hortic Res
Hao X, Li W, Cao H, Tang F, Ma T, Zhang J, Zhang L, Chen L, Jin Z, Pei Y.   +9 more
europepmc   +1 more source

MicroRNA biogenesis is broadly disrupted by inhibition of the splicing factor SF3B1. [PDF]

Nucleic Acids Res
Downie Ruiz Velasco A, Parsons AL, Heatley MC, Martin ARG, Smart AD, Shah N, Jopling CL.   +6 more
europepmc   +1 more source

The RNA splicing factor PRPF8 is required for left-right organiser cilia differentiation and determination of cardiac left-right asymmetry via regulation of Arl13b splicing

Jiang F, Boylan M, Maxwell DW, Qureshi WMS, Rowlands CF, Tenin G, Mitchell K, Stephen LA, Vasconcelos EJ, Wang D, Chen T, Zha J, Liu J, Althali N, Leordean DV, Gallagher MT, Basu B, Szymanska K, Veeraghanta A, Keavney B, Humphries MJ, Ellingford JM, Smith D, Johnson CA, O'Keefe RA, Roy S, Hentges KE.   +26 more
europepmc   +1 more source

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Selective degradation of splicing factor CAPERα by anticancer sulfonamides.

Nature Chemical Biology, 2017
Target-protein degradation is an emerging field in drug discovery and development. In particular, the substrate-receptor proteins of the cullin-ubiquitin ligase system play a key role in selective protein degradation, which is an essential component of ...
Taisuke Uehara, Y. Minoshima, K. Sagane, N. Sugi, K. Mitsuhashi, Noboru Yamamoto, H. Kamiyama, Kentaro Takahashi, Y. Kotake, Mai Uesugi, A. Yokoi, A. Inoue, Taku Yoshida, Miyuki Mabuchi, A. Tanaka, T. Owa   +15 more
semanticscholar   +1 more source

Splicing factor mutant myelodysplastic syndromes: Recent advances.

Advances in Biological Regulation, 2019
The myelodysplastic syndromes (MDS) are common myeloid malignancies showing frequent progression to acute myeloid leukemia (AML). Pre-mRNA splicing is an essential cellular process carried out by the spliceosome.
A. Pellagatti, J. Boultwood
semanticscholar   +1 more source

SRSF5 functions as a novel oncogenic splicing factor and is upregulated by oncogene SRSF3 in oral squamous cell carcinoma.

Biochimica et biophysica acta. Molecular cell research, 2018
Alternative splicing of precursor messenger RNA has been increasingly associated with tumorigenesis. The serine/arginine-rich protein (SR) family plays key roles in the regulation of pre-mRNA alternative splicing.
Sisi Yang, R. Jia, Z. Bian
semanticscholar   +1 more source

The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1

Nature Cell Biology, 2017
Ji-hang Yuan, Xiao-ning Liu, Tian‐tian Wang, W. Pan, Qi‐fei Tao, Weiping Zhou, Fang Wang, Shuhan Sun   +7 more
semanticscholar   +1 more source