Results 11 to 20 of about 74,782 (138)

Ankylosing Spondylitis: a trade Off of HLA-B27, ERAP, and pathogen interconnections? Focus on Sardinia [PDF]

, 2019
The frequency of HLA-B27 in patients with Ankylosing Spondylitis (AS) is over 85%. There are more than 170 recognized HLA-B27 alleles but the majority of them is not sufficiently represented for genetic association studies.
Cauli, A, Fiorillo, Mt, Mathieu, A, Paladini, F, Sorrentino, R., Tedeschi, V   +5 more
core   +2 more sources

Co-Occurrence and Characteristics of Patients With Axial Spondyloarthritis Who Meet Criteria for Fibromyalgia : Results From a UK National Register [PDF]

, 2017
The British Society for Rheumatology (BSR) Biologics Register in Ankylosing Spondylitis is funded by the BSR and they have receive funds for this from Pfizer, AbbVie and UCB.
Atzeni, Fabiola, Barnish, Maxwell S, Haywood, Kirstie L, Jones, Gareth T, MacFarlane, Gary J, Martin, Kathryn R, Packham, Jonathan, Pathan, Ejaz, Siebert, Stefan   +8 more
core   +2 more sources

Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study [PDF]

, 2013
<p>Background: Fatigue is a major component of living with ankylosing spondylitis (AS), though it has been largely over-looked, and currently there are no specific agreed management strategies.</p> <p>Methods: This qualitative ...
A Calin, A van Tubergen, B Belza, D Cote-Arsenault, E Dernis-Labous, Elizabeth Irvine, H Dagfinrud, H Repping-Wuts, Helen Davies, J Kabat-Zinn, J Kabat-Zinn, J Trendall, KGA Adams, MD Atkinson, MG Swain, Michael Dennis, MM Ward, MP Davis, N Aissaoui, National Institute for Health and Clinical Excellence, P Burnard, P Grossman, R Gunaydin, RE Boyatzis, Roxanne Cooksey, S Brophy, S Council:, S Garrett, S Hewlett, S Hultgren, SC Richards, SD Jones, SDH Brophy, Sinead Brophy, Stefan Siebert, Welsh Assembly Government, WH Koh, Y Ibn Yacoub, Y Turan   +38 more
core   +2 more sources

Expression analysis of HLA-E and NKG2A and NKG2C receptors points at a role for natural killer function in ankylosing spondylitis [PDF]

, 2018
Background. Ankylosing Spondylitis (AS) is a complex chronic inflammatory disease strongly associated with the majority of HLA-B27 alleles. HLA-E are non-classical MHC class I molecules that specifically interact with the natural killer receptors NKG2A ...
Angioni, Mm, Cauli, A, Congia, M, Dessole, G, Fiorillo, Mt, Floris, A, Mascia, E, Mathieu, A., Paladini, F, Piga, M, Pinna, S, Sorrentino, R, Tedeschi, V   +12 more
core   +1 more source

Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]

, 2017
INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K., Mantravadi, Santhi, Ogdie, Alexis   +2 more
core   +2 more sources

Single-Cell Genetic Mapping of Gasdermin Expression Across Immune-Mediated Inflammatory Diseases. [PDF]

FASEB J
This figure illustrates the lineage‐specific causal effects of gasdermin (GSDM) expression on the risk of eight immune‐mediated inflammatory diseases (IMIDs). The analysis, based on single‐cell genetic data, shows how GSDMA, GSDMB, and GSDMD affect disease risk in various immune cell types, highlighting distinct protective or risk‐enhancing roles in ...
Gao X, Guo X, Yin K, Jin X.
europepmc   +2 more sources

Treatment recommendations for psoriatic arthritis [PDF]

, 2008
Objective: To develop comprehensive recommendations for the treatment of the various clinical manifestations of psoriatic arthritis (PsA) based on evidence obtained from a systematic review of the literature and from consensus opinion.
Boehncke, Wolf-Henning, Fiorentino, David, FitzGerald, Oliver, Gladman, Dafna D., Gottlieb, Alice B., Helliwell, Philip, Kavanaugh, Arthur, McHugh, Neil J., Mease, Philip J., Nash, Peter, Qureshi, Abrar A., Ritchlin, Christopher T., Soriano, Enrique R., Taylor, William J., Vlam, Kurt de   +14 more
core   +3 more sources

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Sex differences in medication discontinuation in axial spondyloarthritis.

Arthritis Care &Research, Accepted Article.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or Janus kinase inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis [PDF]

, 1993
In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents.
Borg, Andrew A., Dawes, Peter T., Hothersall, T.E.   +2 more
core