Results 111 to 120 of about 54,453 (265)

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Coexistence of Ankylosing Spondylitis, Metabolic Syndrome and Gout Disease [PDF]

Ankylosing spondylitis (AS) and gout are inflammatory diseases causing arthritis. Metabolic syndrome (MetS) is characterized by insulin resistance accompanied by systemic disorders, such as abdominal obesity, glucose intolerance or diabetes mellitus ...
Erkan Kozanoğlu, Meryem Andırın
core   +1 more source

Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis, Sandra Philipp, Thomas Mosch, Björn Fritz, Robert Sabat   +4 more
wiley   +1 more source

Erectile dysfunction in ankylosing spondylitis patients

International Brazilian Journal of Urology
Background Rheumatic diseases such as ankylosing spondylitis (AS) may be associated with sexual dysfunction. Aim To study erectile function of a group of Brazilian AS patients comparing them with controls.
Thiago Santana, Thelma Skare, Vitor Steil Delboni, Juliana Simione, Ana Paula B. Campos, Renato Nisihara   +5 more
doaj   +1 more source

Impact of socioeconomic status on disability in a longitudinal rheumatoid arthritis cohort

Internal Medicine Journal, EarlyView.
Abstract The impact of socioeconomic status (SES) on health outcomes in Australians living with rheumatoid arthritis (RA) is not known. We aimed to determine whether differences in disability trajectory were present according to individuals' SES using longitudinal data from the Australian Rheumatology Association Database.
Oscar Russell, Susan Lester, Jessica Stanhope, Rachel J. Black, Marissa Lassere, Claire Barrett, Lyn March, Tom Lynch, Rachelle Buchbinder, Catherine L. Hill   +9 more
wiley   +1 more source

The role of HLA-B27 in inflammatory arthritis [PDF]

, 2009
Redacted electronic version excludes material for which permission has not been granted by the rights holderThe MHC class I allele, HLA-B27, is strongly associated with a group of inflammatory arthritic conditions collectively known as ...
Lynch, Sarah Janice
core  

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Quality of life in patients with Ankylosing Spondylitis in Duhok government, Kurdistan of Iraq

Advanced Medical Journal
Background and objectives: Spondylarthritis is a broad spectrum of chronic inflammatory diseases, and one of its of phenotypes is ankylosing spondylitis.
Nahida Zuber Ali, Muhammed Tahir Rasool   +1 more
doaj   +1 more source

Toxoplasmosis Beyond Transplantation: Diagnostic and Prevention Challenges in a Patient Receiving Targeted Immunomodulators

Transplant Infectious Disease, EarlyView.
ABSTRACT Toxoplasmosis has long been recognized as a serious complication in immunocompromised host, particularly those with advanced HIV/AIDS, hematopoietic stem‐cell transplantation (HSCT), solid‐organ transplant (SOT), and hematological malignancies. The rapid expansion of targeted immunomodulators, including chimeric antigen receptor T‐cell (CAR‐T)
Joy Mouanes‐Abelin, Christelle Pomares, José G. Montoya, Morgane Pondrom, Lucille DE MARIA, Andrea J. Zimmer, Carlos A. Gomez   +6 more
wiley   +1 more source

Transthoracic Echocardiography findings in patients with Ankylosing Spondylitis in Kurdistan region

Advanced Medical Journal
Background and objectives: Ankylosing spondylitis is a chronic inflammatory disorder that affecting axial and non-axial joints leads to a loss of mobility and function over time.
Elaf Kamal Abdulwahab, Dashty Abbas Albustany   +1 more
doaj   +1 more source