Results 121 to 130 of about 62,107 (256)

Multi‐Omics Insights Into Circulating T‐Cell Metabolic Reprogramming and Treg Dysfunction in Moyamoya Disease

MedComm, Volume 7, Issue 11, November 2026.
The comprehensive study design is illustrated. A multi‐omics approach was used to characterize T‐cell metabolic alterations in MMD. By integrating mass cytometry (CyTOF), single‐cell RNA sequencing (scRNA‐seq), bulk RNA‐seq, metabolomics, and flow cytometry, we aimed to elucidate metabolic reprogramming in circulating T cells and Treg dysfunction in ...
Zhiyao Zheng, Qiheng He, Xinyu Ma, Bojian Zhang, Junsheng Li, Chenglong Liu, Siqi Mou, Wei Sun, Xiangjun Shi, Wenjing Wang, Dong Zhang, Peicong Ge, Jizong Zhao   +12 more
wiley   +1 more source

Aberrant expression of microRNAs in T cells from patients with ankylosing spondylitis contributes to the immunopathogenesis

, 2014
Ankylosing spondylitis (AS) is a chronic inflammatory disorder characterized by dysregulated T cells. We hypothesized that the aberrant expression of microRNAs (miRNAs) in AS T cells involved in the pathogenesis of AS.
Lai, N. -S.;Yu, H. -C.;Chen, H. -C.;Yu, C. -L.;Huang, H. -B.;Lu, M. -C., 余家利   +1 more
core  

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

Co-existance of Juvenil Ankylosing Spondylitis with Familial Mediterranean Fever and Takayasu’s Arteritis: A Case Report

, 2018
Juvenile ankylosing spondylitis (JAS) coexisting with Familial Mediterranean Fever (FMF) or Takayusu’s arteritis (TA) together with JAS have been reported in the literature. However, co-existance of these three diseases has not been reported yet.
Gülcan Gürer, Betül Sargın
core   +1 more source

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome

Neurourology and Urodynamics, Volume 45, Issue 8, Page 1687-1691, November 2026.
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari, Mallory Pine, Viktoriya Sapkalova, Emily Chan Brodowsky, Charles R. Powell, Ramzy T. Burns   +5 more
wiley   +1 more source

DO POSTURAL CHANGES AFFECT BALANCE IN PATIENTS WITH ANKYLOSING SPONDYLITIS?

, 2017
Objective: To investigate the effect on balance control of postural changes related to ankylosing spondylitis. Design: Thirty-four subjects with ankylosing spondylitis and 34 healthy individuals were enrolled.
Balevi Batur, Elif and Kaymak Karatas, Gulcin, Balevi Batur, E., Balevi Batur, Elif, Kaymak Karatas, GÜLÇİN KAYMAK, G Karataş, Kaymak Karatas, G., E Batur   +6 more
core   +1 more source

Janus Kinase Inhibitor Use Among People With Inflammatory Disease in Australia

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Aim To describe Australian trends in JAKi uptake, where there are no restrictions on the sequence of their use in clinical practice. Methods We included all people aged 18 years and over initiating a JAKi between 1 October 2015 and 31 August 2022.
Claire T. Deakin, Michael O. Falster, Geoffrey O. Littlejohn, Peter Youssef, David Liew, Nicole L. Pratt, Sallie‐Anne Pearson   +6 more
wiley   +1 more source

Diagnostic Delay in Ankylosing Spondylitis: Related Factors and Prognostic Outcomes

The Turkish Journal of Gastroenterology, 2016
Objectives: This study aims to evaluate diagnostic delay, factors which are related to diagnostic delay, and the effect of diagnostic delay on prognostic outcomes in terms of spinal and hip mobility, functional status, disease activity, quality of life,
Sasan FALLAHI, Ahmad Reza JAMSHIDI
doaj  

Staged Lateral Lumbar Interbody Fusion Targeting Driver and Compensatory Structural Segments for Adult Degenerative Scoliosis: A Novel Strategy and Early Outcomes

Orthopaedic Surgery, Volume 18, Issue 11, Page 2405-2416, November 2026.
Targeting driver and structural vertebrae via LLIF is an effective, minimally invasive strategy for ADS. It offers substantial deformity correction, symptom relief, and progressive postoperative self‐correction while significantly reducing surgical trauma compared to traditional long‐segment fusions.
Tianyong Wen, Liukun Xu, Peng Lu, Yang Zhang, Wei Ji, Yang Zheng, Zhicheng Zhang, Tiansheng Sun   +7 more
wiley   +1 more source

Robotic‐Arm Assisted Direct Anterior Approach Total Hip Arthroplasty Facilitates Tensor Fasciae Latae Preservation and Early Functional Recovery in Obese Patients

Orthopaedic Surgery, Volume 18, Issue 11, Page 2463-2479, November 2026.
In obese patients undergoing DAA‐THA, RA technology significantly reduced intraoperative injury to TFL. This muscle preservation effect was significantly associated with attenuated early postoperative inflammation, lower pain levels, and faster functional recovery.
Shijie Chen, Dasheng Lin, Huihuang Chen, Wentao Lin, Dongmin Xu, Eryou Feng   +5 more
wiley   +1 more source