Results 141 to 150 of about 54,453 (265)

Associations of blood cell indices with the risk of ankylosing spondylitis: A retrospective case-control and machine learning modeling study

SAGE Open Medicine
Background: Ankylosing spondylitis often presents with nonspecific symptoms, making the identification of high-risk individuals challenging in clinical practice. Objective: This study aimed to utilize blood cell indices to construct interpretable machine
Rongqing He, Kechang He, Xiaopeng Qin, Jie Ma, Zhuo Chen, Boli Qin, Jiang Xue, Tianyou Chen, Jiarui Chen, Xinli Zhan, Chong Liu   +10 more
doaj   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, Volume 183, Issue 15, Page 4111-4125, August 2026.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Ankylosing spondylitis: Bath ankylosing spondylitis disease activity and radiology indeces [PDF]

, 2002
Ankylosing spondylitis is a progressive inflammatory disease of the spine and large joints producing ankylosis and deformity in which evaluation of the disease activity is quite difficult.
ÇETİN, ALP, ÖZÇAKAR, LEVENT, DİNÇER, FİTNAT, Ertürk, Hakan   +3 more
core  

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Illness Experiences of Young Women With Rheumatoid Arthritis in South Korea

Health Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Background Rheumatoid arthritis affects young women during critical life‐course stages, requiring ongoing adaptation to illness‐related uncertainty while managing social roles and expectations. Women in their 20s to 40s face distinctive challenges related to illness disclosure, stigma and life‐course tasks, particularly around childbirth and ...
Wonhee Baek, Hyunjung Doo
wiley   +1 more source

Anxiety and depression correlate with disease and quality-of-life parameters in Chinese patients with ankylosing spondylitis

Patient Preference and Adherence, 2016
Xujuan Xu,1,* Biyu Shen,2,3,* Aixian Zhang,4 Jingwei Liu,3 Zhanyun Da,4 Hong Liu,4 Zhifeng Gu4 1Department of Nursing, Affiliated Hospital of Nantong University, 2School of Nursing, Nantong University, 3Department of Nursing, The Second Affiliated ...
Xu X, Shen B, Zhang A, Liu J, Da Z, Liu H, Gu Z   +6 more
doaj  

Beyond Sequence: Posttranslational Remodeling of Antigens in Autoimmunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT Autoimmune responses are often attributed to failed tolerance to self‐proteins, yet protein expression alone cannot explain why certain antigens dominate disease, why autoreactivity emerges under stress, or why specific HLA alleles shape risk.
Cynthiya Shrestha, Holly M. Weisfelder, Thanh D. Do   +2 more
wiley   +1 more source

Risk of urinary tract infection with SGLT2 inhibitor initiation in patients with immune‐mediated inflammatory diseases and type 2 diabetes: A target trial emulation using a Japanese hospital‐based claims database

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1310-1321, August 2026.
In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima, Nobuyuki Yajima, Takashi Nomiyama, Ryoko Sakai, Hisashi Noma, Akira Katagiri, Naoto Tamura   +6 more
wiley   +1 more source

Comparative analysis of whole spine and sacroiliac joint magnetic resonance SPARCC scores in patients with SAPHO syndrome and ankylosing spondylitis. [PDF]

Front Immunol
Shen Y, Gu X, Yang J, Zhou M, Lin Z, Wang R, Liu J, Guo M, Li C, Zhu Q, He D.   +10 more
europepmc   +1 more source

Interrater Reliability of the Ankylosing Spondylitis Performance Index in Patients With Axial Spondyloarthritis. [PDF]

Musculoskeletal Care
Rasmussen CA, Mink SB, Primdahl J, Knak KL.   +3 more
europepmc   +1 more source