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The Genetics of Spondyloarthritis [PDF]
The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases with common features in terms of clinical presentation and genetic predisposition. SpA is characterized by inflammation of the spine and peripheral joints, and is also be associated with extra-articular inflammatory manifestations such as psoriasis, uveitis, or ...
Roberto Díaz-Peña +4 more
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Epidemiology of Spondyloarthritis [PDF]
Spondyloarthritis (SpA) represents a group of interrelated diseases with common clinical features and a close association with HLA-B27. Reports of incidence and prevalence of diseases vary depending on methodological differences between studies, the case definition used to classify disease, and the prevalence of HLA-B27 in the population studied. Newly
Stolwijk, Carmen +3 more
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The term axial spondyloarthritis covers both non-radiographic disease and radiographic disease (also known as ankylosing spondylitis). Some studies have been performed to investigate the prevalence of axial spondyloarthritis, although most are limited to patients with radiographic disease.
Joachim, Sieper +3 more
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Epigenetics of spondyloarthritis
Spondyloarthritis (SpA) is a chronic inflammatory disorder resulting from a combination of genetic predisposition and environmental factors. Despite recent advances, a substantial fraction of its genetic basis remains poorly understood. Several mechanisms have been proposed to account for this unexplained heritability, including epigenetics which can ...
Cherqaoui, Bilade +5 more
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Juvenile spondyloarthritis [PDF]
This article provides a comprehensive update of the pathogenesis, diagnostic imaging, treatments, and disease activity measurements of juvenile spondyloarthritis (JSpA).Genetic and microbiome studies have provided new information regarding possible pathogenesis of JSpA.
Sabrina, Gmuca, Pamela F, Weiss
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Spectrum of Spondyloarthritis [PDF]
Spondyloarthritis (SpA) comprises a group of related diseases which share similar pathogenesis and clinical manifestations. Although the occurrence of SpA spectrum disorders has been known for some time, it was only in the latter half of the twentieth century that the concept of SpA was formally defined.
Pathak, Himanshu, Gaffney, Karl
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Axial spondyloarthritis (axSpA) is a common name for the non-radiographic form of the disease and radiographic axial spondyloarthritis, known as ankylosing spondylitis (AS). The disease is typically manifested at a young age, characterized by affection of axial skeleton, and in the most severe form can lead to complete ankylosis of the spine.
Leona, Procházková +2 more
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Spondyloarthritis, Acute Anterior Uveitis, and Fungi: Updating the Catterall–King Hypothesis
Spondyloarthritis is a common type of arthritis which affects mostly adults. It consists of idiopathic chronic inflammation of the spine, joints, eyes, skin, gut, and prostate. Inflammation is often asymptomatic, especially in the gut and prostate.
Martin Laurence +5 more
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Classifications and imaging of juvenile spondyloarthritis
Juvenile spondyloarthritis may be present in at least 3 subtypes of juvenile idiopathic arthritis according to the classification of the International League of Associations for Rheumatology.
Iwona Sudoł-Szopińska +5 more
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Inflammatory bowel disease (IBD) is seen in up to 14% of patients with spondyloarthritis (SpA) with a lower prevalence seen in the Asian population. Conversely, SpA is the most common extraintestinal manifestation in IBD, with prevalence ranging from 10% to 39%.
Muhammed Hafis, Vikas Agarwal
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