Results 21 to 30 of about 56,684 (289)

ASAS consensus definition of early axial spondyloarthritis

Annals of the Rheumatic Diseases, 2023
Objectives To develop a consensual definition for the term ‘early axial spondyloarthritis—axSpA’—and ‘early peripheral spondyloarthritis—pSpA’. Methods The ASAS (Assessment of SpondyloArthritis international Society-Spondyloarthritis EARly definition ...
V. Navarro-Compán, D. Benavent, D. Capelusnik, D. van der Heijde, Robert B. M. Landewé, D. Poddubnyy, A. V. van Tubergen, X. Baraliakos, F. E. Van den Bosch, F. V. van Gaalen, L. Gensler, C. López-Medina, H. Marzo-Ortega, A. Moltó, R. Perez-Alamino, M. Rudwaleit, M. van de Sande, R. Sengupta, U. Weber, S. Ramiro   +19 more
semanticscholar   +1 more source

Axial spondyloarthritis [PDF]

Nature Reviews Disease Primers, 2015
The term axial spondyloarthritis covers both non-radiographic disease and radiographic disease (also known as ankylosing spondylitis). Some studies have been performed to investigate the prevalence of axial spondyloarthritis, although most are limited to patients with radiographic disease.
Joachim, Sieper, Jürgen, Braun, Maxime, Dougados, Dominique, Baeten   +3 more
openaire   +4 more sources

Bimekizumab treatment in patients with active axial spondyloarthritis: 52-week efficacy and safety from the randomised parallel phase 3 BE MOBILE 1 and BE MOBILE 2 studies

Annals of the Rheumatic Diseases, 2023
Objectives Bimekizumab (BKZ), a monoclonal IgG1 antibody that selectively inhibits interleukin (IL)-17F in addition to IL-17A, has demonstrated superior efficacy versus placebo in patients with non-radiographic (nr-) and radiographic (r-) axial ...
X. Baraliakos, A. Deodhar, D. van der Heijde, M. Magrey, W. Maksymowych, Tetsuya Tomita, Huji Xu, U. Massow, C. Fleurinck, Alicia M Ellis, T. Vaux, J. Shepherd-Smith, Alexander Marten, L. Gensler   +13 more
semanticscholar   +1 more source

Interleukin-17–targeted treatment in patients with spondyloarthritis and associated cardiometabolic risk profile

Frontiers in Immunology, 2023
Spondyloarthritis is a group of immune-mediated rheumatic disorders that significantly impact patients’ physical function and quality of life. Patients with spondyloarthritis experience a greater prevalence of cardiometabolic disorders, such as obesity ...
Rubén Queiro, Rubén Queiro, Elena Aurrecoechea, Elena Aurrecoechea, Sara Alonso Castro, Ignacio Villa Blanco, Ignacio Villa Blanco, Anahy Brandy-Garcia, Raquel Linge   +8 more
doaj   +1 more source

Epigenetics of spondyloarthritis

Joint Bone Spine, 2020
Spondyloarthritis (SpA) is a chronic inflammatory disorder resulting from a combination of genetic predisposition and environmental factors. Despite recent advances, a substantial fraction of its genetic basis remains poorly understood. Several mechanisms have been proposed to account for this unexplained heritability, including epigenetics which can ...
Cherqaoui, Bilade, Crémazy, Frédéric, Hue, Christophe, Garchon, Henri-Jean, Breban, Maxime, Costantino, Félicie   +5 more
openaire   +3 more sources

Efficacy and safety of biological DMARDs: a systematic literature review informing the 2022 update of the ASAS-EULAR recommendations for the management of axial spondyloarthritis

Annals of the Rheumatic Diseases, 2022
Objective To update the evidence on efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in patients with axial spondyloarthritis (axSpA) to inform the 2022 update of the Assessment of SpondyloArthritis international Society ...
C. Webers, A. Ortolan, A. Sepriano, L. Falzon, X. Baraliakos, Robert B. M. Landewé, S. Ramiro, D. van der Heijde, E. Nikiphorou   +8 more
semanticscholar   +1 more source

Juvenile spondyloarthritis [PDF]

Current Opinion in Rheumatology, 2015
This article provides a comprehensive update of the pathogenesis, diagnostic imaging, treatments, and disease activity measurements of juvenile spondyloarthritis (JSpA).Genetic and microbiome studies have provided new information regarding possible pathogenesis of JSpA.
Sabrina, Gmuca, Pamela F, Weiss
openaire   +2 more sources

Cardiovascular risk in axial spondyloarthritis—a systematic review

Clinical Rheumatology, 2023
Cardiovascular manifestations are common in patients suffering axial spondyloarthritis and can result in substantial morbidity and disease burden.
Rainer Hintenberger, Barbara Affenzeller, Valeriia Vladychuk, H. Pieringer   +3 more
semanticscholar   +1 more source

Axial Spondyloarthritis after bariatric surgery: a 7-year retrospective analysis

Advances in Rheumatology, 2019
Background In recent decades, obesity has become a public health problem in many countries. The objective of this study was to evaluate the main joint and extra-articular manifestations related to spondyloarthritis (SpA) after bariatric surgery (BS) in a
Thauana Luiza de Oliveira, Hilton Telles Libanori, Marcelo M. Pinheiro   +2 more
doaj   +1 more source

Shared and Distinct Gut Microbiota in Spondyloarthritis, Acute Anterior Uveitis, and Crohn's Disease

Arthritis & Rheumatology, 2023
Spondyloarthritis (SpA) is a group of immune‐mediated diseases highly concomitant with nonmusculoskeletal inflammatory disorders, such as acute anterior uveitis (AAU) and Crohn's disease (CD). The gut microbiome represents a promising avenue to elucidate
Morgan Essex, V. Rios Rodriguez, J. Rademacher, F. Proft, U. Löber, Lajos Markó, Uwe Pleyer, Till Strowig, Jérémy Marchand, J. Kirwan, B. Siegmund, S. Forslund, Denis Poddubnyy   +12 more
semanticscholar   +1 more source