Results 71 to 80 of about 4,998,282 (269)

Spontaneous Nambu-Goldstone Currents Generation Driven by Mismatch

, 2006
We review recent progress of understanding and resolving instabilities driven by mismatch between the Fermi surfaces of the pairing quarks in 2-flavor color superconductor.
Huang, Mei
core   +2 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria

Acta Dermato-Venereologica
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predictors
Yingyi Li, Rui Peng, Jingwen Xue, Yi Zhao   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nonlinear characterisation of a silicon integrated Bragg waveguide filter

, 2018
Bragg waveguides are promising optical filters for pump suppression in spontaneous Four-Wave Mixing (FWM) photon sources. In this work, we investigate the generation of unwanted photon pairs in the filter itself.
Baehr-Jones, Tom, Bajoni, Daniele, Bergamasco, Nicola, Galland, Christophe, Galli, Matteo, Harris, Nicholas C., Hochberg, Michael, Liscidini, Marco, Massara, Micol Previde, Menotti, Matteo   +9 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Sensory feedback synchronizes motor and sensory neuronal networks in the neonatal rat spinal cord

Nature Communications, 2016
Spontaneous movements are important for mammalian development but how network activity underlies the generation of these actions remains unclear. Here the authors show that both spontaneous twitches and complex movements enable correlated activity in ...
Ana R. Inácio, Azat Nasretdinov, Julia Lebedeva, Roustem Khazipov   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Emilia: An Extensive, Multilingual, and Diverse Speech Dataset For Large-Scale Speech Generation [PDF]

Spoken Language Technology Workshop
Recent advancements in speech generation models have been significantly driven by the use of large-scale training data. However, producing highly spontaneous, human-like speech remains a challenge due to the scarcity of large, diverse, and spontaneous ...
Haorui He, Zengqiang Shang, Chaoren Wang, Xuyuan Li, Yicheng Gu, Hua Hua, Liwei Liu, Chen Yang, Jiaqi Li, Peiyang Shi, Yuancheng Wang, Kai Chen, Pengyuan Zhang, Zhizheng Wu   +13 more
semanticscholar   +1 more source