Results 101 to 110 of about 1,239,617 (330)

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Spontaneous Symmetry Breaking and Chance [PDF]

, 2002
In this paper I explore the nature of spontaneous symmetry breaking in connection with a cluster of interrelated concepts such as Curie's symmetry principle, chance, and ...
Liu, Chuang
core  

Optophys/Spontaneous:

, 2021
Code for "Spontaneous activity competes with externally evoked responses in sensory ...
Optophysiology Lab
core   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Mouse germ line mutations due to retrotransposon insertions

Mobile DNA, 2019
Transposable element (TE) insertions are responsible for a significant fraction of spontaneous germ line mutations reported in inbred mouse strains. This major contribution of TEs to the mutational landscape in mouse contrasts with the situation in human,
Liane Gagnier, Victoria P. Belancio, Dixie L. Mager   +2 more
doaj   +1 more source

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Characterisation of the spontaneous mutations in AtxA.

, 2015
*The AtxA domains were defined according to (Hammerstrom et al., 2011) WH, Winged Helix-turn-helix; HTH, Mga-like Helix-Turn-helix; PRD, PhosphoTransferase Regulation Domain.**SNP, Single Nucleotide Polymorphism; INS, Insertion; DEL, deletion; VNTR ...
Evelyne Couture-Tosi (466002), Christophe Brézillon (641029), Angelika Lander (716027), Fabian H. Leendertz (111360), Michèle E. Mock (716028), Michel Haustant (716026), Tatjana Franz (72154), Jean-Philippe Corre (188323), Marc Monot (86864), Silke R. Klee (246495), Roland Grunow (246510), Susann Dupke (246501), Gregory Jouvion (3173691), Pierre L. Goossens (188363)   +13 more
core   +1 more source

Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability [PDF]

, 2014
Overgrowth disorders are a heterogeneous group of conditions characterized by increased growth parameters and other variable clinical features such as intellectual disability and facial dysmorphism1.
Baralle, Diana, Tatton-Brown, Katrina, Silvana del Vecchio Duarte, Katrina Tatton-Brown, Sheila Seal, Jenny Harmer, Dabir, Tabib, Diana Baralle, Seal, Sheila, Ramsay, Emma, Robert van Montfort, Goudie, David, Lise Aksglaede, Van Maldergem, Lionel, Selicorni, Angelo, Yachelevich, Naomi, Ajith Kumar, Pilz, Daniela T, Temple, I. Karen, Blanca Gener, Eleanor O'Brien, Zachariou, Anna, Aksglaede, Lise, Angelo Selicorni, Anna Zachariou, David Goudie, Temple, Karen I., Lionel Van Maldergem, Nazneen Rahman, Elise Ruark, del Vecchio Duarte, Silvana, Kumar, Ajith, Harmer, Jenny, I Karen Temple, Gener, Blanca, van Montfort, Robert, Sandra Hanks, Pilz, Daniela T., Hanks, Sandra, Temple, I Karen, Tessa Homfray, Tabib Dabir, O'Brien, Eleanor, Emma Ramsay, Ruark, Elise, Homfray, Tessa, Daniela T Pilz, Rahman, Nazneen, Naomi Yachelevich   +48 more
core   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Spontaneous Mutations in Saccharomyces cerevisiae mtDNA Increase Cell-to-Cell Variation in mtDNA Amount. [PDF]

Int J Mol Sci, 2023
Potapenko EY, Kashko ND, Knorre DA.
europepmc   +1 more source