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Spontaneous and Induced Mutation
Nature, 1953IN his book “Bacterial Physiology” (New York, 1951), Dr. J. Lederberg writes, on page 94: “Not all workers have accepted the duality of adaptation mechanisms. Hinshelwood (1946), for example, has disregarded the selection of spontaneous mutants as an element of bacterial adaptations, apparently in order to bolster the applicability of his system of ...
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Origin of Spontaneous Mutations
Nature, 1933SPONTANEOUS mutations are generally supposed to be induced by some unknown external agent. However, it may be expected that mutation is influenced also by certain intracellular processes which develop automatically and may be created or accelerated by artificial means (for example, by X-rays).
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2020
There is a long-standing interest in the study of mutations—from the quest to enhance evolutionary inference related to the genetic underpinnings of disease, to the improvement of our understanding of the chronology of human evolution, to characterizing relationships between species.
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There is a long-standing interest in the study of mutations—from the quest to enhance evolutionary inference related to the genetic underpinnings of disease, to the improvement of our understanding of the chronology of human evolution, to characterizing relationships between species.
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Dependence of induced mutation on spontaneous mutation in Tribolium castaneum
Nature, 1976IN plants the effect of physical and chemical mutagens has been found to depend on the frequency of spontaneous mutation1,2, but no such information is available from animal material. I have therefore investigated the relationship between spontaneous and X-ray-induced somatic mutation in the flour beetle Tribolium castaneum. This relationship was found
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1970
Inasmuch as heritable changes are primarily caused by mutations affecting individual cistrons within the genome, the accurate estimation of the spontaneous mutation rate is of the utmost importance in understanding evolution. Furthermore, in view of the fact that a mutation randomly affects a single base pair of any cistron and that only some of the ...
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Inasmuch as heritable changes are primarily caused by mutations affecting individual cistrons within the genome, the accurate estimation of the spontaneous mutation rate is of the utmost importance in understanding evolution. Furthermore, in view of the fact that a mutation randomly affects a single base pair of any cistron and that only some of the ...
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