Specific early electroencephalogram for the diagnosis of sporadic Creutzfeldt-Jakob disease [PDF]
PrionAn early diagnosis is required for intervention in prion disease cases. To elucidate the specificity of early electroencephalography discharges in cases of sporadic Creutzfeldt-Jakob disease, we analysed epileptiform discharges through ...
Taiki Matsubayashi +5 more
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Progressive multifocal diffusion-weighted imaging hyperintensities in sporadic Creutzfeldt–Jakob disease with positive cerebrospinal fluid real-time quaking-induced conversion: a case report [PDF]
Journal of Medical Case ReportsBackground Creutzfeldt–Jakob disease is a rare and invariably fatal neurodegenerative disorder classified among the prion diseases. Primarily affecting the brain, this condition precipitates neuronal cell demise, culminating in swiftly advancing dementia
Puyu Li +6 more
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Sporadic Creutzfeldt–Jakob disease in Palestine with early ataxia and dysarthria: a case report [PDF]
BMC NeurologyCreutzfeldt–Jakob disease (CJD) is a rare and fatal neurodegenerative disorder caused by misfolded prion proteins. It progresses inexorably to death once clinical symptoms emerge.
Anita S. Bahbah +4 more
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Atypical Presentation of Sporadic Creutzfeldt–Jakob Disease in a 59-Year-Old Male Patient [PDF]
BJPsych OpenAims: Creutzfeldt–Jakob Disease (CJD) is a rare, fatal neurodegenerative disorder caused by prion proteins, leading to progressive brain damage. CJD has sporadic, variant, genetic, and iatrogenic forms, with sporadic being the most common, affecting 1–2 ...
Ruzaika Jaufer
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A Case of sporadic Creutzfeldt-Jakob disease [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2023 Fatma Şimşek, Recep Yevgi
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Developing neuropalliative care for sporadic Creutzfeldt-Jakob Disease
Prion, 2022 We aimed to identify targets for neuropalliative care interventions in sporadic Creutzfeldt-Jakob disease by examining characteristics of patients and sources of distress and support among former caregivers.
Krista L. Harrison +6 more
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Subtype and Regional-Specific Neuroinflammation in Sporadic Creutzfeldt–Jakob Disease [PDF]
Frontiers in Aging Neuroscience, 2014 The present study identifies deregulated cytokines and mediators of the immune response in the frontal cortex and cerebellum of sporadic Creutzfeldt-Jakob disease (sCJD) MM1 and VV2 subtypes compared to age-matched controls. Deregulated genes include pro- and anti-inflammatory cytokines, toll-like receptors, colony stimulating factors, cathepsins ...
Llorens, Franc +7 more
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Viruses, 2021 In the present manuscript, we report the clinical presentation and challenging diagnostic work-up of a sporadic Creutzfeldt–Jakob disease patient with confirmed VV1 subtype and heterozygous 1-octapeptide repeat deletion in the prion protein gene.
Aušrinė Areškevičiūtė +4 more
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Acta Neuropathologica Communications, 2020 Mitochondrial dysfunction has been implicated in multiple neurodegenerative diseases but remains largely unexplored in Creutzfeldt-Jakob disease. Here, we characterize the mitochondrial respiratory chain at the individual neuron level in the MM1 and VV2 ...
Irene H. Flønes +7 more
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Diagnostic approach in a patient with Creutzfeldt-Jakob disease [PDF]
Dementia & Neuropsychologia, 2022 Prion diseases are an important cause of rapidly progressive dementias. Among them, the most common is sporadic Creutzfeldt-Jakob disease (CJD). It is a rare and incurable disease, with rapid progression to death.
José Wagner Leonel Tavares-Júnior +9 more
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