Results 41 to 50 of about 5,104,410 (171)

Evidence for a pathogenic role of different mutations at codon 188 of PRNP [PDF]

, 2008
Clinical and pathological changes in familial Creutzfeldt-Jakob disease (CJD) cases may be similar or indistinguishable from sporadic CJD. Therefore determination of novel mutations in PRNP remains of major importance.
Eva-Maria Grasbon-Frodl, Hans A Kretzschmar, Roeber, Sigrun, Arzberger, Thomas, Sigrun Roeber, Weber Petra, Krebs, Bjarne, Schröter, Andreas, Petra Weber, Illig, T., Zerr, I., Schröter, A., Arzberger, T., Illig Thomas, Windl, Otto, Bjarne Krebs, Wei Xiang, Hans A. Kretzschmar, Schroeter, Andreas, Kretzschmar, H.A., Inga Zerr, Grasbon-Frodl, Eva-Maria, Weber, Petra, Windl, O., Zerr, Inga, Schröter Andreas, Kretzschmar, Hans A., Xiang, W., Xiang Wei, Illig, Thomas, Zerr Inga, Thomas Illig, Vollmert, C., Grasbon-Frodl Eva-Maria, Kretzschmar Hans A., Caren Vollmert, Weber, P., Krebs Bjarne, Grasbon-Frodl, E.M., Krebs, B., Vollmert Caren, Vollmert, Caren, Roeber Sigrun, Xiang, Wei, Arzberger Thomas, Roeber, S., Windl Otto, Andreas Schröter, Otto Windl, Thomas Arzberger   +49 more
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CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis. [PDF]

, 2012
The cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and ...
Oeckl, Patrick, Albert C Ludolph, Hans A Kretzschmar, Ludolph, Albert C., Markus Otto, Kretzschmar, Hans A., Petra Steinacker, Stefan Lehnert, Ferger Boris, Patrick Oeckl, Otto, Markus, Ferger, Boris, Oeckl Patrick, Ludolph Albert C., Boris Ferger, Steinacker, Petra, Otto Markus, Lehnert Stefan, Steinacker Petra, Kretzschmar Hans A., Jesse, Sarah, Lehnert, Stefan, Sarah Jesse, Jesse Sarah   +23 more
core   +1 more source

Public health concerns regarding sporadic Creutzfeldt–Jakob disease in China: a case series

Journal of International Medical Research, 2019
In this study, we report three cases of sporadic Creutzfeldt–Jakob disease in China, two confirmed cases and one probable case. The aim of this study was to enrich the data regarding clinical and epidemiological features of this disease and to provide ...
Ru-Yi Zhou, Yinzhu Zhou, Heng Zhang, Qingqing Hu, Jinjie Zhu, Jin Zhao, Shuilian Chen, Ruchun Liu, Weihong Hu, Xixing Zhang, Xianfa Xuan, Yuxue Liao, Tianmu Chen   +12 more
doaj   +1 more source

Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob disease [PDF]

, 2005
In recent studies, the amyloid form of recombinant prion protein (PrP) encompassing residues 89-230 (rPrP 89-230) produced in vitro induced transmissible prion disease in mice.
Bocharova, O V, Salnikov, V V, Gill, A C, Vadim V. Salnikov, Ilia V. Baskakov, Leonid Breydo, Breydo, L, Olga V. Bocharova, Andrew C. Gill, Baskakov, I V   +9 more
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Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid [PDF]

, 2005
Background: There is evidence that homocysteine contributes to various neurodegenerative disorders. Objective: To assess the values of homocysteine in patients with Creutzfeldt-Jakob disease (CJD) in both cerebrospinal fluid (CSF) and plasma.
Bleich, S., Kropp, S., Wiltfang, J., Zerr, Inga, Zerr, I., Kretzschmar, Hans A., Kropp, Silke, Otto, Markus, Wiltfang, Jens, Bleich, Stefan   +9 more
core   +1 more source

Young-onset sporadic Creutzfeldt–Jakob disease with atypical phenotypic features: a case report

Journal of Medical Case Reports, 2019
Background Sporadic Creutzfeldt–Jakob disease, with a mean survival of 6 months, is duly considered among the most fatal neurological disorders. Rapidly progressive dementia with multi-axial involvement of the nervous system is the known presentation ...
Durjoy Lahiri, Srimant Pattnaik, Ashwani Bhat, Souvik Dubey, Atanu Biswas, Biman Kanti Roy   +5 more
doaj   +1 more source

Bioassay studies support the potential for iatrogenic transmission of variant Creutzfeldt Jakob Disease through dental procedures [PDF]

, 2012
<p>Background: Evidence is required to quantify the potential risks of transmission of variant Creutzfeldt Jakob (vCJD) through dental procedures. Studies, using animal models relevant to vCJD, were performed to address two questions.
Elizabeth Kirby (115076), Marsh, PD, Raven, N.D.H., Mark Cornwall, Andrew Smith (11197), Marsh Philip D., Vassey, M., Neil McLeod (115085), Cornwall Mark, Joanne Dickinson (115078), J. Mark Sutton (115091), Cornwall, M, Dickinson, J., Dickinson Joanne, Vassey Matthew, Mark Cornwall (115083), Raven, NDH, Matthew Vassey (115080), Mike Dennis, Walker, J.T., Kirby Elizabeth, Smith, A, McLeod, N., J Mark Sutton, Walker, JT, Dennis, M., Sutton, J.M., Matthew Vassey, Philip D. Marsh (115087), James T Walker, Marsh, P.D., Dennis, M, Joanne Dickinson, McLeod Neil, McLeod, N, Andrew Smith, Walker James T., Elizabeth Kirby, Raven Neil D. H., Smith, A., Vassey, M, Neil D. H. Raven (115095), James T. Walker (115089), Dickinson, J, Sutton, JM, Sutton J. Mark, Kirby, E, Kirby, E., Smith Andrew, Neil McLeod, Cornwall, M., Mike Dennis (115082), Philip D Marsh, Neil D H Raven, Dennis Mike   +54 more
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Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease [PDF]

, 2009
Several molecular subtypes of sporadic Creutzfeldt-Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype.
Summers, DM, Collins, S.J. (Steven), Brandel, J.P., Meissner, B, Meissner, B., Cras, P. (Patrick), Varges, D., Jansen, GH, Cras, Patrick, Pimentel, J, Brandel, J P, Smith, P., Taratuto, Ana Lia, van Duijn, Cornelia M., Begue, Christian, Summers, D. M., Summers, D.M., Jansen, G. H., Hewer, Ekkehard, Ladogana, Anna, Jansen, Gerard H, Will, Robert G., Schuur, M. (Maaike), Haik, S., Sanchez-Juan, P. (Pascual), Begue, C, Brandel, JP, Collins, S J, Heinemann, U., Haik, Stephane, Stokin, G B, Zerr, I., Schuur, M, Pimentel, Jose, Breithaupt, M., Taratuto, A, Sanchez-Juan, P, van Duijn, C., Stokin, GB, Breithaupt, Maren, Collins, SJ, Kallenberg, K., Sanchez-Juan, P., Collie, Donald A., Sanchez-Juan, Pascual, Hewer, E, Ladogana, A. (Anna), Schuur, M., Romero, C, Tikka-Kleemola, P. (Päivi), Cras, P., Schuur, Maaike, Romero, Carlos, Ladogana, A, Haik, S, Duijn, Cornelia, Stokin, G. B., Taratuto, A., Collie, D, Stokin, G.B., Brandel, J. P., Romero, C., Smith, P, Jansen, G H, Collie, D., Begue, C., Heinemann, U, Will, R G, Smith, Pete, Pocchiari, M., Collins, S. J., Pocchiari, Mauricio, Ladogana, A., Will, R. G., Will, RG, Meissner, Bettina, Summers, D M, Breithaupt, M, Jansen, G.H. (Gerard), Kallenberg, Kai, Hewer, E., Will, R.G., Cras, P, Zerr, I, Roberts, H., Jansen, Gerard H., Pocchiari, M, van Duijn, C, Pocchiari, M. (Maurizio), Varges, Daniel. A., Roberts, H, Brandel, Jean-Philippe, Kallenberg, K, Varges, D, Pimentel, J., et al.   +95 more
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Clinical Features of Rapidly Progressive Alzheimer's Disease [PDF]

, 2010
Objective: To characterize clinical features, CSF biomarkers and genetic polymorphisms of patients suffering from a rapidly progressing subtype of Alzheimer's dementia (rpAD).
Meissner, Bettina, Bettina Meissner, Zerr, Inga, Redyk, Katharina, Christian Schmidt, Nico von Ahsen, Kretzschmar, Hans A., Lennart Krack, Schmidt, Christian, Roeber, Sigrun, von Ahsen, Nico, Katharina Redyk, Sigrun Roeber, Hans Kretzschmar, Inga Zerr, Krack, Lennart, Kretzschmar, Hans, Schmidt, Christian D., Krack, Lennart A., Ahsen, Nico von   +19 more
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Early Remission of Cerebrospinal Fluid Interleukin‐6 After Initial Immunotherapy Predicts a Good Prognosis in Autoimmune Encephalitis

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro, Yuto Uchida, Hiroyasu Inoue, Toyohiro Sato, Teppei Fujioka, Masayuki Mizuno, Shoji Kawashima, Masahiro Oomura, Noriyuki Matsukawa   +8 more
wiley   +1 more source