Results 41 to 50 of about 6,976 (171)
White matter involvement in sporadic Creutzfeldt-Jakob disease [PDF]
, 2014 Sporadic Creutzfeldt-Jakob disease is considered primarily a disease of grey matter, although the extent of white matter involvement has not been well described.
DeArmond, Stephen J +11 more
core +2 more sources
Neurology and Clinical Neuroscience, EarlyView.ABSTRACT Background Autoimmune encephalitis therapy requires adjusting the regimen based on therapeutic response; however, clinical indicators of this response remain unknown. Aim To determine the predictive capability of cerebrospinal fluid (CSF), electroencephalography (EEG), and brain magnetic resonance imaging (MRI) in identifying responders to ...
Yuta Madokoro +8 more
wiley +1 more source
BMC Public Health, 2005 Background Epidemiological studies on the potential role of surgery in Creutzfeldt-Jakob Disease transmission have disclosed associations with history of specific surgical interventions or reported negative results.
Calero Miguel +5 more
doaj +1 more source
The first reported case of Creutzfeldt‐Jakob disease from Nepal
Clinical Case Reports, 2020 Creutzfeldt‐Jakob disease (CJD) can also be diagnosed in a resource‐limited setting through good clinical analysis. The diagnosis of CJD should be considered in patients with rapidly evolving neurological signs associated with cognitive disturbances even
Himal Kharel +4 more
doaj +1 more source
From Meat to Plant‐Based Products? The Enduring Impact of BSE on Beef Consumption
Agricultural Economics, Volume 57, Issue 4, July 2026.ABSTRACT This study reassesses the impact of the historical BSE outbreak on EU diets, showing that consumption patterns shifted persistently even after policy actions eliminated the food safety risk. Utilizing advanced difference‐in‐differences techniques on 1980–2020 data, we demonstrate that while beef consumption exhibited a transient U‐shaped ...
Jader Velásquez, Shon Ferguson
wiley +1 more source
A case of sporadic Creutzfeldt-Jakob disease [PDF]
Romanian Journal of Neurology, 2012 Sporadic Creutzfeldt-Jakob disease (CJD) is a very rare and fatal disease caused by prions – proteins with unique characteristics and infective potential.
Raoul Pop +5 more
doaj +1 more source
HaloTag Fusion Enables Dynamic Analysis of Prion Protein Biosynthesis, Turnover, and Misfolding
ChemBioChem, Volume 27, Issue 11, 15 June 2026.Prion protein (PrP) misfolding underlies fatal neurodegenerative diseases. We developed a HaloTag‐based PrP fusion enabling spatiotemporal labeling of distinct PrP populations in living cells. This system recapitulates native PrP biology, reveals early misfolding events in disease‐associated mutants, and allows mechanistic interrogation of PrP‐lowering
Antonio Masone +2 more
wiley +1 more source
Case Reports in Neurological Medicine, 2018 Sporadic Creutzfeldt-Jakob disease (sCJD) is a type of progressive, subacute encephalopathy associated with spongiform degeneration of the central nervous system.
Sira Carrasco García de León +3 more
doaj +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1088-1105, June 2026.ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Extraneural pathologic prion protein in sporadic Creutzfeldt-Jakob disease. [PDF]
, 2003 BACKGROUND: In patients with sporadic Creutzfeldt-Jakob disease, pathologic disease-associated prion protein (PrPSc) has been identified only in the central nervous system and olfactory-nerve tissue. Understanding the distribution of PrPSc in Creutzfeldt-
Glatzel, M +3 more
core +1 more source