Clostridioides Difficile Spore: Coat Assembly and Formation [PDF]
Emerging Microbes and Infections, 2022 Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming, toxin-producing, obligate anaerobic bacterium. C. difficile infection (CDI) is the leading cause of healthcare-associated infective diarrhoea.
Guo-Bao Tian, Ji Zeng, Min Dong
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Architecture and assembly of the Bacillus subtilis spore coat. [PDF]
PLoS ONE, 2014 Bacillus spores are encased in a multilayer, proteinaceous self-assembled coat structure that assists in protecting the bacterial genome from stresses and consists of at least 70 proteins.
Marco Plomp +3 more
doaj +6 more sources
Real-time nanoscale investigation of spore coat assembly in Bacillus subtilis [PDF]
Communications BiologySpores of Bacillaceae, ubiquitous in soil, can withstand extreme conditions virtually indefinitely. The spore coat, one of the most sophisticated multiprotein complexes built by bacteria, protects the spore from environmental stresses and predators.
Armand Lablaine +3 more
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Disruption of Spore Coat Integrity in Bacillus subtilis Enhances Macrophage Immune Activation [PDF]
Current Issues in Molecular BiologyProbiotics play a pivotal role in animal production by promoting growth, enhancing gut health, and modulating immune responses. Bacillus subtilis, a widely utilized probiotic, forms robust spores that exhibit exceptional resistance, making it ideal for ...
Bolang Liao +6 more
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The Conserved Spore Coat Protein SpoVM Is Largely Dispensable in
mSphere, 2017 The spore-forming bacterial pathogen Clostridium difficile is a leading cause of health care-associated infections in the United States. In order for this obligate anaerobe to transmit infection, it must form metabolically dormant spores prior to exiting
John W. Ribis +4 more
doaj +3 more sources
The influence of sporulation conditions on the spore coat protein composition of Bacillus subtilis spores. [PDF]
Frontiers in Microbiology, 2016 Spores are of high interest to the food and health sectors because of their extreme resistance to harsh conditions, especially against heat. Earlier research has shown that spores prepared on solid agar plates have a higher heat resistance than those ...
Wishwas R. Abhyankar +9 more
doaj +7 more sources
Role of the Spore Coat Proteins CotA and CotB, and the Spore Surface Protein CDIF630_02480, on the Surface Distribution of Exosporium Proteins in Clostridioides difficile 630 Spores [PDF]
Microorganisms, 2022 Clostridioides difficile is Gram-positive spore-former bacterium and the leading cause of nosocomial antibiotic-associated diarrhea. During disease, C. difficile forms metabolically dormant spores that persist in the host and contribute to recurrence of ...
Nicolás Montes-Bravo +5 more
doaj +2 more sources
Interactions of Bacillus subtilis Basement Spore Coat Layer Proteins [PDF]
Microorganisms, 2021 Bacillus subtilis endospores are exceptionally resistant cells encircled by two protective layers: a petidoglycan layer, termed the cortex, and the spore coat, a proteinaceous layer.
Daniela Krajčíková +2 more
doaj +2 more sources
Identification of SpoVID as a putative new substrate of the sporulation-specific protease YabG in Bacillus subtilis [PDF]
Frontiers in MicrobiologyBacillus subtilis YabG, a cysteine protease expressed in mother cells during sporulation, is involved in the processing of spore coat proteins. However, the full spectrum of YabG substrates and the physiological significance of its proteolytic activity ...
Ritsuko Kuwana +3 more
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Reliable delineation of Clostridioides difficile and related members of the family Peptostreptococcaceae using phylogenomics and spore coat protein-specific molecular markers [PDF]
Microbiology SpectrumTraditional bacterial classification relies on phenotypic traits (e.g., morphology and metabolic profiles), but these methods lack resolution for closely related taxa and are biased by culture conditions.
Jianying Han +4 more
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