Clostridioides difficile spore: coat assembly and formation [PDF]
Emerging Microbes and Infections, 2022 Clostridioides difficile (C. difficile) is a Gram-positive, spore-forming, toxin-producing, obligate anaerobic bacterium. C. difficile infection (CDI) is the leading cause of healthcare-associated infective diarrhoea.
Ji Zeng +3 more
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The influence of sporulation conditions on the spore coat protein composition of Bacillus subtilis spores. [PDF]
Frontiers in Microbiology, 2016 Spores are of high interest to the food and health sectors because of their extreme resistance to harsh conditions, especially against heat. Earlier research has shown that spores prepared on solid agar plates have a higher heat resistance than those ...
Wishwas R. Abhyankar +9 more
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Role of the Spore Coat Proteins CotA and CotB, and the Spore Surface Protein CDIF630_02480, on the Surface Distribution of Exosporium Proteins in Clostridioides difficile 630 Spores [PDF]
Microorganisms, 2022 Clostridioides difficile is Gram-positive spore-former bacterium and the leading cause of nosocomial antibiotic-associated diarrhea. During disease, C. difficile forms metabolically dormant spores that persist in the host and contribute to recurrence of ...
Nicolás Montes-Bravo +5 more
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Interactions of Bacillus subtilis Basement Spore Coat Layer Proteins [PDF]
Microorganisms, 2021 Bacillus subtilis endospores are exceptionally resistant cells encircled by two protective layers: a petidoglycan layer, termed the cortex, and the spore coat, a proteinaceous layer.
Daniela Krajčíková +2 more
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Architecture and assembly of the Bacillus subtilis spore coat. [PDF]
PLoS ONE, 2014 Bacillus spores are encased in a multilayer, proteinaceous self-assembled coat structure that assists in protecting the bacterial genome from stresses and consists of at least 70 proteins.
Marco Plomp +3 more
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The Conserved Spore Coat Protein SpoVM Is Largely Dispensable in
mSphere, 2017 The spore-forming bacterial pathogen Clostridium difficile is a leading cause of health care-associated infections in the United States. In order for this obligate anaerobe to transmit infection, it must form metabolically dormant spores prior to exiting
John W. Ribis +4 more
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Disruption of Spore Coat Integrity in Bacillus subtilis Enhances Macrophage Immune Activation [PDF]
Current Issues in Molecular BiologyProbiotics play a pivotal role in animal production by promoting growth, enhancing gut health, and modulating immune responses. Bacillus subtilis, a widely utilized probiotic, forms robust spores that exhibit exceptional resistance, making it ideal for ...
Bolang Liao +6 more
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Real-time nanoscale investigation of spore coat assembly in Bacillus subtilis [PDF]
Communications BiologySpores of Bacillaceae, ubiquitous in soil, can withstand extreme conditions virtually indefinitely. The spore coat, one of the most sophisticated multiprotein complexes built by bacteria, protects the spore from environmental stresses and predators.
Armand Lablaine +3 more
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Assessment of chemical methods in the extraction of spore surface layers in Clostridioides difficile spores [PDF]
mSphereClostridioides difficile spores are essential for initiation, recurrence, and transmission of C. difficile infections (CDI). These outermost layers of the spore, the exosporium and spore coat, are responsible for initial interactions with the host and ...
Javier Sanchez +6 more
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Diverse supramolecular structures formed by self-assembling proteins of the Bacillus subtilis spore coat. [PDF]
Mol Microbiol, 2015 Bacterial spores (endospores), such as those of the pathogens Clostridium difficile and Bacillus anthracis, are uniquely stable cell forms, highly resistant to harsh environmental insults.
Jiang S +6 more
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