Results 71 to 80 of about 55,988 (224)

MoLAEA Regulates Secondary Metabolism in Magnaporthe oryzae

open access: yesmSphere, 2020
Fungi are rich sources of secondary metabolites of pharmaceutical importance, such as antibiotics, antitumor agents, and immunosuppressants, as well as of harmful toxins.
Pallabi Saha   +2 more
doaj   +1 more source

SPORULATING ANAEROBES ON ENGLISH FLAX [PDF]

open access: yesJournal of Applied Bacteriology, 1953
Summary: A microaerophilic plectridium identified as Clostridium pectinovorum , and Cl. butyricum , were the major sporulating organisms found on English flax. Both these organisms were non‐pectolytic and unable to ret flax.
openaire   +2 more sources

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

open access: yesThe FEBS Journal, EarlyView.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar   +3 more
wiley   +1 more source

Prediction of Sporulation and Germination by the Spider Mite Pathogenic Fungus Neozygites floridana (Neozygitomycetes: Neozygitales: Neozygitaceae) Based on Temperature, Humidity and Time

open access: yesInsects, 2018
Neozygites floridana is a pathogenic fungus and natural enemy of the two-spotted spider mite, Tetranychus urticae (Acari: Tetranychidae), which is an important polyphagous plant pest.
Thiago Castro   +4 more
doaj   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

open access: yesImmunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang   +7 more
wiley   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta   +5 more
wiley   +1 more source

A Small Molecule-Screening Pipeline to Evaluate the Therapeutic Potential of 2-Aminoimidazole Molecules Against Clostridium difficile

open access: yesFrontiers in Microbiology, 2018
Antibiotics are considered to be the first line of treatment for mild to moderately severe Clostridium difficile infection (CDI) in humans. However, antibiotics are also risk factors for CDI as they decrease colonization resistance against C.
Rajani Thanissery   +3 more
doaj   +1 more source

Staurosporine Targets Mitochondrial Regulator VdAtuA3 to Disrupt Mitochondrial Homeostasis to Control Verticillium Wilt

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Mitochondria serve as cellular powerhouses that generate ATP via electron transport chain complexes and orchestrate metabolism‐apoptosis cross‐talk, yet genes maintaining mitochondrial homeostasis remain underexplored as antifungal targets. In this study, a previously uncharacterised protein VdAtuA3 was identified as a novel interactor with ...
Ruo‐Cheng Sheng   +10 more
wiley   +1 more source

Mevalonate Diphosphate Decarboxylase MVD/Erg19 Is Required for Ergosterol Biosynthesis, Growth, Sporulation and Stress Tolerance in Aspergillus oryzae

open access: yesFrontiers in Microbiology, 2019
Mevalonate diphosphate decarboxylase (MVD; EC 4.1.1.33) is a key enzyme of the mevalonic acid (MVA) pathway. In fungi, the MVA pathway functions as upstream of ergosterol biosynthesis, and MVD is also known as Erg19.
Yunlong Sun   +9 more
doaj   +1 more source

Genetic and Phenotypic Diversity of European Triticale: GWAS of Yellow Rust Resistance and Agronomic Traits

open access: yesPlant Breeding, EarlyView.
ABSTRACT Triticale (x Triticosecale Wittmack) is an interspecific hybrid of wheat and rye. It is a promising grain and forage crop that thrives in poorer soils and low‐input farming systems. It can serve as a viable alternative to traditional small grains such as wheat and barley, bringing diversity to crop rotations and enhancing biodiversity in ...
Riccardo Zustovi   +17 more
wiley   +1 more source

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