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Sex-specific reference intervals of hematologic and biochemical analytes in Sprague-Dawley rats using the nonparametric rank percentile method. [PDF]
PLoS ONE, 2017 Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well ...
Qili He +9 more
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PLoS ONE, 2014 Genetic (G) and environmental (E) manipulations are known to alter behavioural outcomes in rodents, however many animal models of neuropsychiatric disorders only use a restricted selection of strain and housing conditions.
Karly M Turner, Thomas H J Burne
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EFFECT OF SMOKING IN INTERLEKIN-6 IN SPRAGUE DAWLEY RATS
Pakistan Armed Forces Medical Journal, 2018 Objective: To investigate the effect of cigarette smoking on interleukin-6 in Sprague Dawley rats. Study Design: Randomized controlled study. Place and Duration of Study: Study was conducted at Army Medical College Rawalpindi, from Jan to Apr 2015 ...
Aneela Jamil +2 more
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Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats
Pharmaceutics, 2022 Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development.
Christine M. Madla +8 more
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Oman Medical Journal, 2022 Objectives: We sought to investigate the healing efficacy of thermosensitive in situ gelling formulation containing metronidazole and diclofenac potassium on ligature-induced periodontitis (LIP) in rats. Methods: We used 30 adult male Sprague-Dawley rats;
Nida M. A. Wadi +2 more
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Hermaphroditism in a Sprague-Dawley Rat [PDF]
Veterinary Pathology, 2007 A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9–week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the ...
R W, Diters +4 more
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Physiological Reports, 2021 Background Local ischemic preconditioning (IPC) and remote ischemic conditioning (RIC) induced by brief periods of ischemia and reperfusion protect against ischemia‐reperfusion injury.
Thomas Ravn Lassen +6 more
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Study on chronic toxicity of rhubarb extract in Sprague-Dawley rats
Heliyon, 2022 Objective: The purpose of this study was to evaluate the safety of rhubarb extract. Methods: SD rats were treated with rhubarb extract at 0, 101, 405 and 1620 mg/kg/day for 52 weeks. food consumption and body weights were recorded.
Wenxiang Yang +7 more
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Biomedicines, 2023 Depression is a psychiatric disorder characterized by a marked decrease in reward sensitivity. By using the olfactory bulbectomy (OBX) model of depression, it was shown that OBX rats display enhanced drug-taking and seeking behaviors in a self ...
Liana Fattore +3 more
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BMC Research Notes, 2010 Background The Dahl salt-sensitive rat, but not the Dahl salt-resistant rat, develops hypertension and hypovitaminosis D when fed a high salt diet. Since the salt-sensitive rat and salt-resistant rat were bred from the Sprague Dawley rat, the aim of this
Bayorh Mohamed A +3 more
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