Results 171 to 180 of about 247,912 (307)

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb–Drug Interaction Investigation

Biopharmaceutics &Drug Disposition, EarlyView.
Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula, Jeevan Sai Kallam, Aarika Kanukolanu, Ganesh Korada, Lakshmi Vineela Nalla   +4 more
wiley   +1 more source

Tridiet-enhanced weight gain in Sprague Dawley rats: a retrospective analysis. [PDF]

Front Nutr
Rodriguez AL, Bradfield C, Scarpa NV, Barroso BE, Fernandez MI, Cabanillas SV, Deleon-Pena A, Frias E, Agboli VI, Sarkar S, Datta S, Schiefer MA.   +11 more
europepmc   +1 more source

Glycoengineered Recombinant Alpha1‐Antitrypsin Results in Comparable In Vitro and In Vivo Activities to Human Plasma‐Derived Protein

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Alpha‐1‐antitrypsin (A1AT) is a multifunctional, clinically important, high‐value therapeutic glycoprotein that can be used for the treatment of many diseases, such as A1AT deficiency, diabetes, graft‐versus‐host disease, cystic fibrosis, and various viral infections. Currently, the only U.S. food and drug administration‐approved treatment for
Frances Rocamora, Chen‐Lin Hsieh, Sanne Schoffelen, Johnny Arnsdorf, Eric A. Toth, Abdul S. Yunus, Thomas E. Cleveland IV, Sara Petersen Bjørn, Mina Ying Min Wu, Noel G. McElvaney, Bjørn Gunnar Rude Voldborg, Thomas R. Fuerst, Nathan E. Lewis   +12 more
wiley   +1 more source

Effects of MDMA treatment and cessation on sexual behaviour and testicular functions in male sprague-dawley rats. [PDF]

BMC Pharmacol Toxicol
Obembe OO, George ET, Mustapha RA, Akhigbe RE.   +3 more
europepmc   +1 more source

Effects of handling and vehicle injections on adrenocorticotropic and corticosterone concentrations in Sprague-Dawley compared with Lewis rats.

, 2015
The hypothalamic-pituitary-adrenal (HPA) axis is a key factor in the trajectory of the addiction-like cycle (a pattern of behavior characterized by escalating drug use, withdrawal, and relapse) in preclinical and clinical studies.
Kreek, Mary Jeanne, Zhou, Yan, Seip-Cammack, Katharine, Picetti, Roberto, Deutsch-Feldman, Molly   +4 more
core  

Beyond wound sealing: A dual‐functional adhesive nanofiber membrane promoting coagulation and osteogenesis in extraction sites

BMEMat, EarlyView.
Inspired by the suction mechanics of octopus suckers, a dual‐layer nanofiber membrane integrates antibacterial protection, strong wet adhesion, and osteogenic support, offering a bioinspired strategy for effective hemostasis and alveolar bone preservation.
Huijing Ma, Liheng Gao, Hao Liang, Wentao Jiang, Junyi Wang, Jiajia Wang, Shuhan Duan, Lingxi Meng, Adilijiang Yimiti, Wenjie Zhang   +9 more
wiley   +1 more source

Pharmacokinetics and preliminary data on safety of meloxicam subcutaneous extended-release formulation in Sprague-Dawley rats. [PDF]

Front Vet Sci
Gupta A, Akkaraju H, Vasudevan V, Turaga S, Rohan LC, Patel SK, Levinson B, Leary S, Witham S, Shaik IH, Venkataramanan R.   +10 more
europepmc   +1 more source

Wild Blueberries Affect Endothelium-dependant Vasodilation in Sprague-Dawley and Spontaneously Hypertensive Rats

, 2007
We examined the effect(s) of wild blueberries on the major vasodilation pathways of Sprague-Dawley and spontaneously hypertensive rats (SHR). Weanling male Sprague-Dawley and SHR were fed a control (C-Sprague-Dawley, HC-SHR) or a blueberry-enriched (B ...
Clark, Kateryna
core  

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

RETRACTION: Gastroprotective Effects of Plants Extracts on Gastric Mucosal Injury in Experimental Sprague-Dawley Rats. [PDF]

Biomed Res Int
Research International B.
europepmc   +1 more source