Results 311 to 320 of about 334,934 (359)
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Prostate cancer in a Sprague‐Dawley rat
The Prostate, 1985AbstractAn adenocarcinoma of the prostate gland developed in one rat of the Lobund Sprague‐Dawley (S‐D) strain, following treatments with testosterone propionate in silastic membranes. The transplanted cells (PA‐SD1) developed local tumors, metastasized through lymphatic channels to the lungs, and induced osteolytic lesions when deposited adjacent to ...
M, Pollard, P H, Luckert
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Leiomyoma of the iris in a Sprague-Dawley rat
Journal of Comparative Pathology, 1987A leiomyoma of the iris was composed of bundles of spindle-shaped cells with abundant myoglial fibres and represents the first observation of this rare tumour in a rat.
R A, Owen, P, Duprat
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Behavioral heterogeneity in Sprague-Dawley rats
Physiology & Behavior, 1992Because of consistent individual differences in animal behavior, it is often difficult to interpret experimental data. We therefore attempted to rank Sprague Dawley rats by a hierarchical ascendant clustering technique using data from avoidance conditioning and open-field testing (scores of exploratory activity before, during, and after an ...
M, Curé, J P, Rolinat
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Postirradiation Sarcomas in Sprague-Dawley Rats
Radiation Research, 1998A series of radiation-induced neoplasms occurred in Sprague-Dawley rats 4-8 months after irradiation of a single hind leg with 60Co gamma rays. The rats were exposed to fractionated cumulative doses that ranged from 0 to 106 Gy. Osteosarcomas, malignant fibrous histiocytomas and fibrosarcomas developed in the radiation fields of a number of the rats in
P T, Tinkey +5 more
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Spontaneous Hibernomas in Sprague-Dawley Rats
Toxicologic Pathology, 2009Hibernomas are rare neoplasms originating in brown adipose tissue of humans and other animal species, including laboratory animals. Background incidence values for these tumors in all common strains of laboratory rats are generally accepted as being <0.1%.
Richard H, Bruner +10 more
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Intrauterine Expression of Prothrombin in the Sprague-Dawley Rat
Journal of the Society for Gynecologic Investigation, 2002Thrombin appears to underlie myometrial contractions in response to intrauterine bleeding. In a similar fashion, thrombin generated within the uterus in the absence of active bleeding could also produce contractions. These studies sought to determine whether functionally active prothrombin is expressed in the pregnant and nonpregnant rat uterus.
Mark, Phillippe +4 more
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Polycystic kidney disease in Sprague-Dawley rats
Experimental and Toxicologic Pathology, 2015Polycystic kidney disease (PKD) is a cystic genetic disorder of the kidneys which is typically associated with cystic bile duct dilatation in the liver in humans, and domestic and laboratory animals. In humans, there are two types of PKD, autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD ...
Ahmed, Shoieb, Norimitsu, Shirai
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Respiration in Sprague-Dawley Rats During Pregnancy
Inhalation Toxicology, 2006Minute ventilation and tidal volume increase in humans during pregnancy. Little data exists, however, on the respiration in pregnant rats, despite their widespread use as an animal model. Since respiration will affect the pharmacokinetics of volatile compounds and ultimately the dose to the fetus, we conducted a study to evaluate respiration in rats ...
Teresa L, Leavens +5 more
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Urinary chemistry of the normal Sprague-Dawley rat
Urological Research, 1993On the basis of metabolic in vivo studies using the adult male Sprague-Dawley rat, we present a comprehensive summary of urine species measurements conducted in our laboratory over the last several years, as well as those present in the literature.
P N, Shevock, S R, Khan, R L, Hackett
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