Results 331 to 340 of about 334,934 (359)
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Spontaneous endocrine tumors in Sprague-Dawley rats
Journal of Cancer Research and Clinical Oncology, 1979Spontaneous endocrine tumors were found in 81 of 100 Sprague-Dawley rats (42 males and 39 females) which survived for more than 2 years. Most of these tumors were medullary carcinomas of the thyroid, followed by tumors of the anterior pituitary gland, pheochromocytomas and cortical adenomas of the adrenal gland, and islet cell tumors of the pancreas ...
H, Suzuki, U, Mohr, G, Kimmerle
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Toxicity Studies of Epichlorohydrin in Sprague-Dawley Rats
Drug and Chemical Toxicology, 1996Adult male and female Sprague-Dawley rats received epichlorohydrin via gavage in distilled water for 10 consecutive days at dose levels of 3, 7, 19, and 46 mg/kg-day, and for 90 days at dose levels of 1, 5, and 25 mg/kg-day. Epichlorohydrin did not adversely effect mortality, but toxicity, at the higher doses, was evident by: 1) losses in body weight ...
F B, Daniel +3 more
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Immunolocalization of Ghrelin in the Stomach of Sprague‐Dawley Rat
Anatomia, Histologia, Embryologia, 2010With 3 figures and 1 tableSummaryTo investigate the distribution of ghrelin in different regions of stomach in Sprague‐Dawley rat, and attempt to compare with those of humans and other mammalian species in this study, the stomach of rats was divided into five sections, cardia, fundus, greater curvature, lesser curvature and pylorus ...
J, Li +6 more
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Carcinogenic Effects of Diisopropanolnitrosamine in Sprague-Dawley Rats
JNCI: Journal of the National Cancer Institute, 1977The carcinogenic effects of diisopropanolinitrosamine (DIPN) were tested in Sprague-Dawley rats and were then compared with results produced earlier by the same substance in Syrian hamsters. In addition to the similarities, several differences were noted; for example, DIPN caused pancreatic tumors in all the hamsters, but only 1 pancreatic tumor was ...
U, Mohr, G, Reznik, P, Pour
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Normal colon of Sprague-Dawley rats
Anatomy and Embryology, 1992The patterns of expression of the human-tumor-associated antigens, CO17-1A, GA73-3, BR55-2, GICA19-9, CA50 and carcino-embryonic antigen (CEA) were studied in the normal colonic mucosa (the last three also in the serum) of Sprague-Dawley rats. Four immunohistochemically different segments were identified: caecum, ascending colon, transverse colon and ...
J D, Shetye, C A, Rubio, H T, Mellstedt
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Lactational transfer of bisphenol A in Sprague–Dawley rats
Toxicology Letters, 2010Bisphenol A (BPA), an important industrial chemical to which humans are exposed on a daily basis, has long been associated with endocrine disruption in experimental animal models. Such exposures are of concern, particularly during fetal and early neonatal periods, because of greater vulnerability of developing organs to aberrant endocrine signaling ...
Daniel R, Doerge +3 more
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Mammary adenolipoma in a female Sprague-Dawley rat
Experimental and Toxicologic Pathology, 1993P G, Germann, H, Ernst
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