Results 41 to 50 of about 330,960 (360)

Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague–Dawley rats

Respiratory Research, 2016
BackgroundThe increasing use of silver nanoparticles (AgNPs) in consumer products is concerning. We examined the potential toxic effects when inhaled in Brown-Norway (BN) rats with a pre-inflammatory state compared to Sprague–Dawley (SD) rats.MethodsWe ...
J. Seiffert, A. Buckley, B. Leo, Nicholas G. Martin, Jie Zhu, Ranran Dai, Farhana Hussain, Chang Guo, J. Warren, A. Hodgson, J. Gong, M. Ryan, J. Zhang, A. Porter, T. Tetley, A. Gow, Rachel Smith, K. Chung   +17 more
semanticscholar   +1 more source

Characterization of Diabetic Neuropathy in the Zucker Diabetic Sprague-Dawley Rat: A New Animal Model for Type 2 Diabetes

Journal of Diabetes Research, 2014
Recently a new rat model for type 2 diabetes the Zucker diabetic Sprague-Dawley (ZDSD/Pco) was created. In this study we sought to characterize the development of diabetic neuropathy in ZDSD rats using age-matched Sprague-Dawley rats as a control.
Eric P. Davidson, Lawrence J. Coppey, Amey Holmes, Sergey Lupachyk, Brian L. Dake, Christine L. Oltman, Richard G. Peterson, Mark A. Yorek   +7 more
doaj   +1 more source

Biometric Data Comparison Between Lewis and Sprague Dawley Rats

Frontiers in Veterinary Science, 2019
Introduction: Pressure mapping systems are often used for indirect assessment of kinematic gait parameter differences after repair of critical peripheral nerve defects in small animal models.
Richard Steiner, Madhu Dhar, Stacy M. Stephenson, Steven Newby, Austin Bow, Alisha Pedersen, David E. Anderson   +6 more
doaj   +1 more source

Acute and chronic toxicities of Bacopa monnieri extract in Sprague-Dawley rats

BMC Complementary and Alternative Medicine, 2016
BackgroundBacopa monnieri is a medicinal plant which has long been used in Ayurvedic medicines to augment brain function and to improve memory. The purpose of our study was to identify and evaluate possible toxic effects of B. monnieri extract in rats by
S. Sireeratawong, K. Jaijoy, P. Khonsung, N. Lertprasertsuk, K. Ingkaninan   +4 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Determination of Biological Activity of Gonadotrophins in Randombred and Sprague Dawley Rats. Part 2. Determination of Biological Activity of Luteinising Hormone

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. The tendency towards reducing the use of laboratory animals in pharmaceutical quality assessment, along with the development of new technologies for gonadotrophin production, necessitate the development of novel assays to determine the ...
T. A. Batuashvili, E. O. Chechetova, P. V. Shadrin, N. P. Neugodova   +3 more
doaj   +1 more source

Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats

Data in Brief, 2018
The synthetic cathinones methylone, butylone, and pentylone differ from each other through the one carbon lengthening of the α-alkyl chain: methylone (-CH3), butylone (-CH2CH3), and pentylone (-CH2CH2CH3) while 3,4-methylenedioxymethamphetamine (MDMA ...
Gregory G. Grecco, David F. Kisor, Jon E. Sprague   +2 more
doaj   +1 more source

Ovarian Neoplasia in the Sprague-Dawley Rat [PDF]

Environmental Health Perspectives, 1987
Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor,
openaire   +2 more sources

Protective Effects of Tamarillo (Cyphomandra betacea) Extract against High Fat Diet Induced Obesity in Sprague-Dawley Rats

Journal of Obesity, 2015
This study aims to investigate the protective effect of Cyphomandra betacea in adult male Sprague-Dawley rats fed with high fat diet. Rats were fed on either normal chow or high fat diet for 10 weeks for obesity induction phase and subsequently received ...
Noor Atiqah Aizan Abdul Kadir, A. Rahmat, H. Jaafar   +2 more
semanticscholar   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source