Results 1 to 10 of about 317,880 (361)
Systemic candidiasis in Sprague-Dawley rats [PDF]
Medical Mycology, 1996 A reproducible model of a generalized Candida albicans infection was established in rats to allow a precise evaluation of the efficacy of antifungal compounds. In contrast to the intravenous C. albicans model in mice, which serves as a primary model for in vivo efficacy studies of antimycotic compounds, the infectious process in Sprague-Dawley rats is ...
Axel Schmidt
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High dietary salt does not significantly affect plasma 25-hydroxyvitamin D concentrations of Sprague Dawley rats [PDF]
BMC Research Notes, 2010 Background The Dahl salt-sensitive rat, but not the Dahl salt-resistant rat, develops hypertension and hypovitaminosis D when fed a high salt diet. Since the salt-sensitive rat and salt-resistant rat were bred from the Sprague Dawley rat, the aim of this
Bayorh Mohamed A +3 more
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Daidzein ameliorates peripheral neuropathy in Sprague Dawley rats [PDF]
Frontiers in PharmacologyNeuropathy is the most common disorder comprising peripheral nerve damage in diabetic patients. Prolonged hyperglycaemia and oxidative stress cause metabolic imbalance and are the key reasons for the development of diabetic neuropathy.
Ankit P. Laddha, Yogesh A. Kulkarni
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Choroidal coloboma in sprague-dawley rats.
Journal of Toxicologic Pathology, 1994 This communication describes 2 cases of choroidal coloboma in untreated Sprague-Dawley rats. On ophthalmoscopical examination, a 4 weeks old female and 11 weeks old male rats had a focal pale area which in both cases were located inferonasal to the optic disc. These pale foci were oval and well-delineated from the surrounding fundus.
Satoru Inagaki +4 more
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Oman Medical Journal, 2022 Objectives: We sought to investigate the healing efficacy of thermosensitive in situ gelling formulation containing metronidazole and diclofenac potassium on ligature-induced periodontitis (LIP) in rats. Methods: We used 30 adult male Sprague-Dawley rats;
Nida M. A. Wadi +2 more
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Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats
Pharmaceutics, 2022 Wistar and Sprague Dawley are the most common strains of rat used in pharmaceutical research and are used interchangeably in pre-clinical drug development.
Christine M. Madla +8 more
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Sex-specific reference intervals of hematologic and biochemical analytes in Sprague-Dawley rats using the nonparametric rank percentile method. [PDF]
PLoS ONE, 2017 Hematologic and biochemical analytes of Sprague-Dawley rats are commonly used to determine effects that were induced by treatment and to evaluate organ dysfunction in toxicological safety assessments, but reference intervals have not been well ...
Qili He +9 more
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Hermaphroditism in a Sprague-Dawley Rat [PDF]
Veterinary Pathology, 2007 A spontaneous case of unilateral true hermaphroditism was observed during the routine necropsy of a 9–week-old presumed female Sprague-Dawley rat on a repeat-dose toxicity study. There were no drug-related effects observed. True hermaphroditism is rare in rats, and despite the large numbers of rats examined annually, few cases are reported in the ...
R. W. Diters +4 more
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Physiological Reports, 2021 Background Local ischemic preconditioning (IPC) and remote ischemic conditioning (RIC) induced by brief periods of ischemia and reperfusion protect against ischemia‐reperfusion injury.
Thomas Ravn Lassen +6 more
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Voluntary Alcohol Intake following Blast Exposure in a Rat Model of Mild Traumatic Brain Injury. [PDF]
PLoS ONE, 2015 Alcoholism is a frequent comorbidity following mild traumatic brain injury (mTBI), even in patients without a previous history of alcohol dependence. Despite this correlational relationship, the extent to which the neurological effects of mTBI contribute
Yi Wei Lim +5 more
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