Results 201 to 210 of about 332,610 (361)

Carbon nanoparticle toxicity assessment in the liver of male Sprague-Dawley rats. [PDF]

open access: yesOpen Vet J
Ahmad B   +6 more
europepmc   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu   +11 more
wiley   +1 more source

Extended One-Generation Reproductive Toxicity (EOGRT) study of benzoic acid in Sprague Dawley rats

open access: hybrid, 2021
Duncan Turnbull   +4 more
openalex   +1 more source

Gel‐Amin for Improving Extracellular Recordings of Cardiomyocytes in a 3D Microphysiological System

open access: yesAdvanced Electronic Materials, EarlyView.
This work combines a conductive collagen‐based hydrogel with a laser‐cut and assembly technique to fabricate microphysiological systems that improve extracellular recordings of cardiomyocytes in 3D on microelectrode arrays. The inclusion of choline acrylate into GelMA imparts a higher electrical conductivity and improves the signal‐to‐noise ratio of on‐
Dominic Pizzarella   +4 more
wiley   +1 more source

Robot‐Assisted Doppler Optical Coherence Tomography for Intraoperative Evaluation of Microvascular Anastomoses

open access: yesAdvanced Intelligent Systems, EarlyView.
This work presents a robot‐assisted Doppler optical coherence tomography system for autonomous, wide‐field intraoperative assessment of microvascular anastomoses. Machine‐vision–guided probe positioning and adaptive scan planning enable three‐dimensional structural and hemodynamic imaging over extended vessel segments.
Xiaochen Li   +10 more
wiley   +1 more source

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