Results 181 to 190 of about 207,451 (211)

Black phosphorus‐based photothermal disruption of cancer‐associated fibroblast barriers and tumor‐associated macrophage targeting to enhance anti‐PD‐L1 immunotherapy in triple‐negative breast cancer

Interdisciplinary Medicine, EarlyView.
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan, Shicui Hong, Xinyue Wang, Yanghang Li, Cai Wang, Yaxiao Liu, Ying Chen, Chen Fang, Yifeng Zheng, Shengqi Wang, Juping Zhang, Neng Wang, Zhiyu Wang   +12 more
wiley   +1 more source

The Absorption, Distribution, Excretion, and In Vitro Hepatic Microsomal Metabolism of the Novel CDK Compound XMD12 in Sprague-Dawley Rats. [PDF]

Pharmaceutics
Zheng XH, Chang YC, Li YH, He YX, Zhao PX, Wang FF, Xu JY, Tan YF.   +7 more
europepmc   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Hepatoprotective Effects and Antioxidant Properties of a Herbal Detoxifying Formula Against Chlorpyrifos-Induced Toxicity in Sprague-Dawley Rats. [PDF]

Biology (Basel)
Kunnaja P, Chansakaow S, Taychaworaditsakul W, Intatham S, Jaijoy K, Wittayapraparat A, Yusuk P, Suksathan R, Sireeratawong S.   +8 more
europepmc   +1 more source

Tannic Acid Mitigates Monosodium Glutamate‐Induced Cortical Damage by Modulating Synaptic and Calcium‐Related Gene and Protein Expression

Journal of Applied Toxicology, EarlyView.
ABSTRACT Neurotoxicity induced by excessive glutamatergic signaling is associated with synaptic dysfunction, calcium imbalance, and oxidative stress, which are key molecular events implicated in several neurodegenerative conditions. Monosodium glutamate (MSG), a common flavor enhancer, may exert neurotoxic effects, particularly on synaptic integrity ...
Medine Sibel Karagac, Enver Fehim Koçpinar, Hamid Ceylan   +2 more
wiley   +1 more source

Serum Pharmacokinetics of a Highly Concentrated Buprenorphine Formulation in Older Female Sprague-Dawley Rats (Rattus norvegicus). [PDF]

J Am Assoc Lab Anim Sci
Galang KG, Knych HK, Oates RS.
europepmc   +1 more source

Expression Patterns of Cav1.3 in the Developing Stria Vascularis of Sprague-Dawley Rats. [PDF]

J Int Adv Otol
Du Z, Liu H, Chu H, Chen J.
europepmc   +1 more source

90-day oral toxicity study of a salmon nasal cartilage extract containing undenatured collagen and proteoglycan in Sprague-Dawley rats. [PDF]

PLoS One
Takada K, Nakano H.
europepmc   +1 more source

Long-term cannabidiol treatment did not restore bone microstructural defects in skeletally mature ovariectomized Sprague-Dawley rats. [PDF]

JBMR Plus
Chanpaisaeng K, Fleet JC, Rawiwet V, Phonsatta N, Panya A, Panupinthu N, Charoenphandhu N.   +6 more
europepmc   +1 more source

Olanzapine-induced metabolic syndrome is partially mediated by oxytocinergic system dysfunction in female Sprague-Dawley rats. [PDF]

PLoS One
Oduor ED, Mwangi PW, Chege BM, Olago SF, Bukachi F.   +4 more
europepmc   +1 more source