Results 171 to 180 of about 908,208 (245)

Effects of MDMA treatment and cessation on sexual behaviour and testicular functions in male sprague-dawley rats. [PDF]

BMC Pharmacol Toxicol
Obembe OO, George ET, Mustapha RA, Akhigbe RE.   +3 more
europepmc   +1 more source

Genome‐wide network analysis identifies the lncRNA‐92467/miR‐205‐5p/PTPRM/CAMs axis in a rat model of hypoxic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of hypoxic pulmonary hypertension (HPH) remains unclear. In this study, we explored its key regulatory mechanisms using animal models, RNA sequencing, and cellular assays. We found that lncRNA‐92467 functions as a ceRNA, binding miR‐205‐5p, and thereby upregulating PTPRM, inhibiting abnormal proliferation and migration of endothelial ...
Yan‐Ying Shen, Yi‐Bing Chen, Xin Li, Xiang Xu, Ge Guo, Han‐Lu Li, Yong‐Ming Yao, Chun‐Lei Liu   +7 more
wiley   +1 more source

Pharmacokinetics and preliminary data on safety of meloxicam subcutaneous extended-release formulation in Sprague-Dawley rats. [PDF]

Front Vet Sci
Gupta A, Akkaraju H, Vasudevan V, Turaga S, Rohan LC, Patel SK, Levinson B, Leary S, Witham S, Shaik IH, Venkataramanan R.   +10 more
europepmc   +1 more source

Carbon nanoparticle toxicity assessment in the liver of male Sprague-Dawley rats. [PDF]

Open Vet J
Ahmad B, Jabeen F, Hassan M, Ikram S, Manan M, Haseeb M, Zahoor MK.   +6 more
europepmc   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

RETRACTION: Gastroprotective Effects of Plants Extracts on Gastric Mucosal Injury in Experimental Sprague-Dawley Rats. [PDF]

Biomed Res Int
Research International B.
europepmc   +1 more source

Aortic valve disease: Novel animal models for advancing our understanding of the underlying mechanisms

Animal Models and Experimental Medicine, EarlyView.
Due to the complex pathophysiology of aortic valve disease (AVD) and the resulting lack of effective pharmacotherapy, existing animal models are valuable research tools, but each has its own strengths and limitations. This review systematically surveys the major AVD models, compares their induction methods, pathological features, advantages and ...
Liya Hou, Xue Liu, Wangxing Hu, Xianbao Liu, Wei Zhu   +4 more
wiley   +1 more source

Acute and subacute oral toxicity assessment of Karanjin in Sprague Dawley rats. [PDF]

Toxicol Rep
Lubau NSA, Balasubramaniam V, Yap CG, Arulsamy A, Subramaniyan V.   +4 more
europepmc   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

Automated spermatogenic staging in periodic acid-Schiff-stained testes of Sprague-Dawley rats using a deep learning model for normal and atrophied tissues. [PDF]

PLoS One
Kim DM, Rho JH, Wee SY, Son HY.
europepmc   +1 more source