Results 191 to 200 of about 908,208 (245)

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Anatomical localization and acupuncture pathway of the sphenopalatine ganglion in Sprague-Dawley rats: a microanatomical study. [PDF]

Front Neurol
Zhao Y, Li L, Yao M, An X, Wang J, Li Z, Dai H, Dai J, Zhang L.   +8 more
europepmc   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Hyperglycemia Induced in Sprague-Dawley Rats Modulates the Expression of CD36 and CD69 During Wound Healing. [PDF]

Int J Mol Sci
Ho V, Tran T, Patel J, Teshome B, Rai V.
europepmc   +1 more source

Multifunctional polycaprolactone‐based composite fibers with icariin and glutathione for effective repair of critical‐sized bone defects

BMEMat, EarlyView.
A multifunctional PCL‐based scaffold co‐delivering Icariin and Glutathione synergistically enhances osteogenesis, angiogenesis, and oxidative stress resistance, achieving near‐complete repair of critical‐sized bone defects in vivo. This cell‐free platform represents a promising strategy for accelerated bone regeneration.
Abdurohman Mengesha Yessuf, Yaqi Zhang, Bharat Prasad Sharma, Yake Wang, Tibebu Shiferaw Kassa, Abdul Qadir, Ye Jinqiu, Mohamedazeem M. Mohideen, Ahmed M. Salama, Weiguo Wang, Qidong Zhang, Yong Liu   +11 more
wiley   +1 more source

Favorable safety and immunogenicity of a combined quadrivalent influenza and recombinant SARS-CoV-2 vaccine in Sprague-Dawley rats for both primary and booster immunization. [PDF]

Front Immunol
Shao J, Zhang C, She G, Qin T, Zhang J, Fang M, Zhao D, Wang L, Xia L, Yang Q, Zhang L, Zhang Y, Zhang S, Wang J, Xie Z, Chen Y, Chen Y, Huang E, Zhang L.   +18 more
europepmc   +1 more source

A biomechanical optimized Zr58Cu25Al14Nb3 bulk metallic glass dental implant improves peri‐implant stress distribution and bone quality under physiological loading

BMEMat, EarlyView.
This study reports a novel Zr58Cu25Al14Nb3 bulk metallic glass that possesses high mechanical strength and low elastic modulus, which further promotes efficient mechanotransduction and significantly improves peri‐implant bone quality upon cyclic occlusal loading.
Yunshu Wu, Feifei Wang, Yuan He, Yaopeng Zhang, Yuhao Zeng, Fu Zheng, Zhanqi Wei, Sukun Tian, Kinon Chen, Baoan Sun, Yuchun Sun   +10 more
wiley   +1 more source

Pharmacokinetics and Neuroprotective Efficacy of Poly-Arginine Peptide R18D in Sprague Dawley Rats Subjected to Transient Intraluminal Filament Middle Cerebral Artery Occlusion Stroke. [PDF]

CNS Neurosci Ther
Meloni BP, Gribble SK, Thomas MG, Weksler A, Finkelstein L, Fishtein L, Kovalchuk D, Maximov G, Schauder A, Kigel-Zur K, Meilin S.   +10 more
europepmc   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Effects of maternal exposure to an adsorbed acellular diphtheria-tetanus-pertussis (reduced-dose) combined vaccine on prenatal and postnatal development in Sprague-Dawley rats: a preclinical study. [PDF]

Front Immunol
Kong W, Chu H, Gu Q, Ma Y, Cai L, Li J, Wang X, Ji Q, Wen J, Gao N, Ji G, Hu W, Zhao T, Ping L, Fu Y, Li Y, Gong T, Jin Y, Yang Y, Fu Y, Qin X, Zheng H, Yang J, Liang J.   +23 more
europepmc   +1 more source