Results 241 to 250 of about 76,841 (314)

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

Advanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge, María Pagnon de la Vega, Silvia Zampar, Enrica Cerilli, Srinivas Koutarapu, Ling Wu, Paul Fraser, Sertan Arkan, Vilmantas Giedraitis, Lars Lannfelt, Greta Hultqvist, Stina Syvänen, Martin Ingelsson, Jörg Hanrieder, Dag Sehlin   +14 more
wiley   +1 more source

Nano-Spray-Drying of Cyclodextrin/Ibuprofen Complexes with Aerosolization-Enhancing Additives for Pulmonary Drug Delivery. [PDF]

Int J Mol Sci
Motzwickler-Németh A, Körmendi E, Farkas Á, Csóka I, Ambrus R.   +4 more
europepmc   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Optimization of Fermentation Conditions for <i>Bacillus amyloliquefaciens</i> JL54 and Preparation of Powder Through Spray Drying. [PDF]

Plants (Basel)
Zhao L, Wang Y, Pan M, Kong W, Wang H, Tan J.   +5 more
europepmc   +1 more source

Liposomal Nanoconfinement Enables Type I Photodynamic Conversion for Synergistic Cancer Photothermal‐Immunotherapy

Advanced Science, EarlyView.
Liposomal nanoconfinement converts the hemicyanine photosensitizer RhM from Type‐II to Type‐I photodynamic therapy (PDT) while enhancing photothermal therapy (PTT). The RhM‐R837@Lip nanoassembly efficiently generates superoxide (O2•−) and hydroxyl radicals (•OH) to kill tumor cells and achieve tumor ablation.
Minglu Zhang, Shanshan Liang, Meng Wang, Tingfeng Zhang, Jinke Liu, Yuyuan Peng, Hao Fang, Lingna Zheng, Xiao He, Meng Wang, Luling Wu, Tony D. James, Wei Zhao, Bing Wang, Weiyue Feng   +14 more
wiley   +1 more source

Viability of Microencapsulated Probiotics in Cross-Linked Alginate Matrices and Chia Seed or Flaxseed Mucilage During Spray-Drying and Storage. [PDF]

Microorganisms
Bustamante M, Oomah BD, Burgos-Díaz C, Vergara D, Flores L, Shene C.   +5 more
europepmc   +1 more source

Use of Natural Polymers for the Encapsulation of Eugenol by Spray Drying. [PDF]

Pharmaceutics
Caballero-Román A, Nardi-Ricart A, Vila R, Cañigueral S, Ticó JR, Miñarro M.   +5 more
europepmc   +1 more source

Comparative Evaluation of Spray-Drying Versus Freeze-Drying Techniques on the Encapsulation Efficiency and Biofunctional Performance of Chenpi Extract Microcapsules. [PDF]

Foods
Zhao J, Qin X, Liu Y, He Q, Qin J, Shen F, Wu Z.   +6 more
europepmc   +1 more source

Synthesis of organic molecules <i>via</i> spray-drying. [PDF]

Chem Sci
Pena G, Albalad J, Maspoch D, Imaz I.
europepmc   +1 more source

Spray dried periodic mesoporous silicas and PMOs applied in chromatography : a comparison [PDF]

, 2011
Ide, Matthias, Lynen, Frederic, Sandra, Patrick, Van Der Voort, Pascal   +3 more
core