Results 71 to 80 of about 52,719 (293)
Quantification of Cell Movement Reveals Distinct Edge Motility Types During Cell Spreading
, 2007 Actin-based motility is central to cellular processes such as migration, bacterial engulfment, and cancer metastasis, and requires precise spatial and temporal regulation of the cytoskeleton.
Harry V. Xenias +8 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On the Potential for Bioenergy and Biofuels from Hydrothermal Vent Microbes [PDF]
Oceanography, 2012 The discovery of deep-sea hydrothermal vents caused scientists to reconsider their notions about life in the deep sea. In these seemingly inhospitable environments, free-living microbes, as well as microbial-animal symbioses, thrive in the warm waters ...
Peter R. Girguis, James F. Holden
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Endeavour Segment of the Juan de Fuca Ridge: One of the Most Remarkable Places on Earth [PDF]
Oceanography, 2012 Endeavour Segment of the Juan de Fuca Ridge is one of three Integrated Study Sites for the Ridge 2000 Program. It is a remarkable, dynamic environment hosting five major hydrothermal fields, numerous smaller fields, and myriad diffuse-flow sites; magma ...
Deborah S. Kelley +14 more
doaj
Defining the characteristics of active spreading centers
, 2012 Senior thesis written for Oceanography 444[Author's Abstract] Spreading centers occur where tectonic plates are moving apart from each other creating new seafloor and mid-oceanic ridges.
Wardell, Catherine
core
, 2023 The divergent rifting/spreading centers and the strike-slip transform faults are the essential tectonic units on Earth, the dynamic evolution of which regulates the development of rifting/spreading basins. The propagation of rifting/spreading centers may
Jiarong Qing (14481603) +6 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Lava Geochemistry as a Probe into Crustal Formation at the East Pacific Rise [PDF]
Oceanography, 2012 Basalt lavas comprise the greatest volume of volcanic rocks on Earth, and most of them erupt along the world's mid-ocean ridges (MORs). These MOR basalts (MORBs) are generally thought to be relatively homogeneous in composition over large segments of the
Michael R. Perfit +8 more
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source