Results 101 to 110 of about 1,843,306 (292)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Distinct Spreading Speeds in a Lotka–Volterra Cooperative System
Journal of Mathematics, 2020 This paper deals with the spreading speeds in the classical Lotka–Volterra cooperative system, of which the bounds have been studied earlier. By introducing an auxiliary cooperative system and constructing an upper solution, we obtain a sufficient condition to confirm two distinct spreading speeds of unknown functions.
openaire +3 more sources
High Speed Blanking: An Experimental Method to Measure Induced Cutting Forces [PDF]
, 2013 Lien vers la version éditeur: http://link.springer.com/article/10.1007/s11340-013-9738-1A new blanking process that involves punch speed up to 10 ms −1 has obvious advantages in increased productivity.
LARUE, Arnaud +5 more
core +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Results in PhysicsThe enhanced spreading of a 2D drop on a stiff and free-standing elastic thin film theoretically investigated by Shanahan (Rev. Phys. Appl. 1988, 23, 1031–1037) has not been studied and verified experimentally. To shed a light on this interesting problem,
Yanbo Yao +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Spatial dynamics of a nonlocal dispersal vector disease model with spatio-temporal delay
Electronic Journal of Differential Equations, 2015 This article concerns the spatial dynamics of a nonlocal dispersal vector disease model with spatio-temporal delay. We establish the existence of spreading speeds and construct some new types of solutions which are different from the traveling wave ...
Jia-Bing Wang +2 more
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Downlink Space–Time Spreading Using Interference Rejection Codes
, 2006 In this paper, the authors will investigate the performance of a loosely synchronized (LS) code-based space–time spreading (STS) scheme in comparison to that of classic Walsh code and pseudonoise code-based STS when communicating over dispersive Nakagami-
Wei, H, Yang, L-L., Hanzo, L
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source