Results 111 to 120 of about 479,813 (291)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Broadband MC DS-CDMA Using Space-Time and Frequency-Domain Spreading

, 2002
In this contribution multicarrier direct-sequence code-division multiple-access (MC DS-CDMA) using space-time spreading (STS) assisted transmit diversity and frequency-domain (F-domain) spreading is investigated in the context of broadband communications
Yang, L-L., Hanzo, L.
core   +1 more source

A discrete time model for epidemic spread: traveling waves and spreading speeds

Communications Faculty Of Science University of Ankara Series A1Mathematics and Statistics, 2017
In this paper, we aim to study spread of an epidemic in a spatiallystratifed population with non-overlapping generations. We consider mean field equation of an endemic chain-binomial process and allow individuals to disperse in the spatial habitat. To be able to model the spatial movement, we used an averaging kernel.
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Integrating Real-Time Meteorological Conditions into a Novel Fire Spread Model for Grasslands

Fire
Accurate comprehension of grassland fires is imperative for maintaining ecological stability. In this study, we propose a novel fire model that incorporates real-time meteorological conditions.
Yakun Zhang, Huimin Yu, Wenjiang Huang, Tiecheng Huang, Meng Fan, Kun Wang   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Multilayer textile-based concept for non-invasive biosensor platform

Fashion and Textiles
The surface area of the working electrode plays a crucial role in determining the sensor’s performance, especially in enzymatic sensors. Increasing the surface area of the working electrode has a significant impact on the sensor’s functionality.
Asril Senoaji Soekoco, Ni Luh Wulan Septiani, Muhammad Iqbal, Irzaman, Widagdo Sri Nugroho, Febdian Rusydi, Nugraha, Brian Yuliarto   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Evaluation of the Possibility of Single-Seed Sowing of Beech Seeds (Fagus Sylvatica l.) with the Use of Pneumatic Sowing Set

Croatian Journal of Forest Engineering, 2016
The aim of the present study was to adapt the pneumatic seeder designed for thick seeds to the sowing of beech seeds and to select appropriate parameters of its operation. In order to evaluate the possibility of sowing particular seeds by the single-seed
Maria Walczykova, Józef Walczyk
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source