Results 91 to 100 of about 479,813 (291)

Coupling the circadian rhythms of population movement and the immune system in infectious disease modeling.

open access: yesPLoS ONE, 2020
The dynamics of infectious diseases propagating in populations depends both on human interaction patterns, the contagion process and the pathogenesis within hosts.
Zhanwei Du, Petter Holme
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Computing Semantic Association: Comparing Spreading Activation and Spectral Association for Ontology Learning [PDF]

open access: yes, 2013
Spreading activation is a common method for searching semantic or neural networks, it iteratively propagates activation for one or more sources through a network { a process that is computationally intensive. Spectral association is a recent technique
Wohlgenannt, Gerhard   +2 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Voltage induced spreading and liquid optical devices [PDF]

open access: yes, 2013
An experimental investigation has been carried out into Liquid dielectrophoresis (LDEP), in which dielectric forces are used to actuate bulk liquid spreading and to imprint a deformation pattern at a liquid air surface.
Sampara, N
core  

Spreading speeds for monostable equations with nonlocal dispersal in space periodic habitats [PDF]

open access: yes, 2020
. The current paper is devoted to the study of spatial spreading dynamics of monostable equations with nonlocal dispersal in spatially periodic habitats. In particular, the existence and characterization of spreading speeds is considered.
Wenxian Shen, Aijun Zhang
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

EXIT Chart Based Joint Code-Rate and Spreading-Factor Optimisation of Single-Carrier Interleave Division Multiple Access [PDF]

open access: yes, 2007
—In this paper, we consider the joint code-rate and spreading-factor optimisation of turbo-style iterative joint detection and decoding assisted single-carrier interleave division multiple access (SC-IDMA) systems using different-rate convolutional codes
Zhang, R, Hanzo, L.
core   +2 more sources

Epidemic spreading in modular time-varying networks

open access: yesScientific Reports, 2018
We investigate the effects of modular and temporal connectivity patterns on epidemic spreading. To this end, we introduce and analytically characterise a model of time-varying networks with tunable modularity. Within this framework, we study the epidemic
Matthieu Nadini   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

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