Results 71 to 80 of about 479,813 (291)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
An Improved Spectrum Model for Sea Surface Radar Backscattering at L-Band
Remote Sensing, 2017 L-band active microwave remote sensing is one of the most important technical methods of ocean environmental monitoring and dynamic parameter retrieval.
Yanlei Du +4 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
A ripple-spreading genetic algorithm for the aircraft sequencing problem [PDF]
, 2011 When genetic algorithms (GAs) are applied to combinatorial problems, permutation representations are usually adopted. Asa result, suchGAsare often confronted with feasibility and memory-efficiency problems.
Di Paolo, Ezequiel A. +3 more
core +1 more source
Superluminal Transmission of Waveguide Mode-Airy Wavepackets
IEEE Photonics Journal, 2012 Here, we propose a way of superluminal transmission of dispersionless wavepackets through waveguides. Our scheme is based on the use of a hybrid wavepacket formed via the association of an Airy wavepacket with a waveguide mode.
Kyoung-Youm Kim
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Spreading speeds for one-dimensional monostable reaction-diffusion equations [PDF]
, 2012 International audienceWe establish in this article spreading properties for the solutions of equations of the type ∂ t u − a(x)∂ xx u − q(x)∂ x u = f (x, u), where a, q, f are only assumed to be uniformly continuous and bounded in x, the nonlinearity f ...
Nadin, Grégoire +3 more
core +1 more source