Results 101 to 110 of about 479,813 (291)
MetalsThis study investigated the influence of spatial orientation on bead morphology and molten pool dynamics during cold metal transfer wire arc additive manufacturing (CMT-WAAM).
Jun Deng +4 more
doaj +1 more source
Spreading speed revisited: Analysis of a free boundary model
Networks & Heterogeneous Media, 2012 We investigate, from a more ecological point of view, a free boundary model considered in [11] and [8] that describes the spreading of a new or invasive species, with the free boundary representing the spreading front. We derive the free boundary condition by considering a "population loss" at the spreading front, and correct some mistakes ...
Gary Bunting +2 more
openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Modeling and Simulating an Epidemic in Two Dimensions with an Application Regarding COVID-19
ComputationWe derive a reaction–diffusion model with time-delayed nonlocal effects to study an epidemic’s spatial spread numerically. The model describes infected individuals in the latent period using a structured model with diffusion.
Khalaf M. Alanazi
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Quantification of Cell Movement Reveals Distinct Edge Motility Types During Cell Spreading [PDF]
, 2007 Actin-based motility is central to cellular processes such as migration, bacterial engulfment, and cancer metastasis, and requires precise spatial and temporal regulation of the cytoskeleton.
Harry V. Xenias +8 more
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Non-contact identification of rotating blade vibration
Mechanical Engineering Journal, 2015 This paper presents a non-contact measurement and diagnostic method for the parametric identification of vibrations of rotating engine blades, based on blade tip-timing (BTT) measured by optical sensors.
Peng WANG +5 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source