Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Mechanism of the NaCl soaking-microwave synergistic pretreatment in suppressing emulsification formation during the aqueous enzymatic extraction of peanut oil. [PDF]
Food Chem XHai N, Lv D, Chen F.
europepmc +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Comparative Assessment of Matrix Integration Dynamics Between Beetroot Powder and Paste in Wheat-Based Cupcake Formulations. [PDF]
Food Sci NutrAgyei-Poku B +3 more
europepmc +1 more source
Temperature-Mediated Gel Texture Transformation in Starch Noodles: In Respect of Glass Transition Temperature T<sub>g</sub>'. [PDF]
GelsLiu H, Hu Q, Yang S, Liu L, Dong X.
europepmc +1 more source
The Effect of an Alternating Magnetic Field-Assisted Freezing Process on the Quality of Frozen Penaeus Japonicus. [PDF]
FoodsYang D, Zhang Q, Xie J, Ding G.
europepmc +1 more source
Functional evaluation of wax-based oleogels as solid fat replacers for designing low saturated fat plant-based meat analogues. [PDF]
NPJ Sci FoodPark YS, Jeong S, Lee S.
europepmc +1 more source