Results 41 to 50 of about 67,191 (295)

StTCP15 regulates potato tuber sprouting by modulating the dynamic balance between abscisic acid and gibberellic acid

Frontiers in Plant Science, 2022
The major stages of the potato life cycle are tuber dormancy and sprouting, however, there is still known very little of the mechanisms that control these processes.
Kaitong Wang, Kaitong Wang, Ning Zhang, Ning Zhang, Xue Fu, Xue Fu, Huanhuan Zhang, Huanhuan Zhang, Shengyan Liu, Shengyan Liu, Xue Pu, Xiao Wang, Huaijun Si, Huaijun Si   +13 more
doaj   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Regulation of blood vessel sprouting [PDF]

Seminars in Cell & Developmental Biology, 2011
Blood vessels are essential conduits of nutrients and oxygen throughout the body. The formation of these vessels involves angiogenic sprouting, a complex process entailing highly integrated cell behaviors and signaling pathways. In this review, we discuss how endothelial cells initiate a vessel sprout through interactions with their environment and ...
John C. Chappell, Victoria L. Bautch, David M. Wiley   +2 more
openaire   +3 more sources

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

Advanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er, Martha Patricia Pérez González, Beatriz Gil Garrido, Jasmine Ho, Hae‐Won Kim, Jonathan Campbell Knowles, Jia Hua, Ferdinand Lali, Prasad Sawadkar   +8 more
wiley   +1 more source

No evidence for age-related alterations in the marmoset retina

Frontiers in Neuroanatomy, 2022
The physiological aging process of the retina is accompanied by various and sometimes extensive changes: Macular degeneration, retinopathies and glaucoma are the most common findings in the elderly and can potentially lead to irreversible visual ...
Silke Haverkamp, Katja Reinhard, Leo Peichl, Matthias Mietsch, Matthias Mietsch   +4 more
doaj   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

NO and ABA Interaction Regulates Tuber Dormancy and Sprouting in Potato

Frontiers in Plant Science, 2020
In plants, nitric oxide synthase (NOS)-like or nitrate reductase (NR) produces nitric oxide (NO), which is involved in releasing seed dormancy. However, its mechanism of effect in potato remains unclear. In this study, spraying 40 μM sodium nitroprusside
Zhike Wang, Rui Ma, Rui Ma, Rui Ma, Mengshi Zhao, Fangfang Wang, Ning Zhang, Huanjun Si, Huanjun Si   +8 more
doaj   +1 more source

Side‐Chains Engineered Self‐Assembly of Ortho‐Benzodipyrrole‐Based Acceptors: Comprehensive Exploration of Structure‐Interface‐Photovoltaics Correlations

Advanced Functional Materials, EarlyView.
The side‐chain configuration in the bay region of C‐shaped ortho‐benzodipyrrole‐based non‐fullerene acceptors plays a crucial role in their self‐assembly, single‐crystal structures, and optoelectronic properties. The closely correlated molecular structure and performance underscore the importance of minimizing A–A self‐aggregation and enhancing D–A ...
Yung‐Jing Xue, Chen‐Yu Chang, Chieh‐Ming Hung, Chi‐Chun Tseng, Je‐Wei Chang, Chun‐Jen Su, Chia‐Lin Tsai, Han‐Cheng Lu, Kuo‐Hsiu Huang, Kuei‐Yu Tai, Chien‐Yi Ku, Chia‐Shing Wu, Su‐Ying Chien, Shang‐Da Yang, Bing‐Huang Jiang, Chih‐Ping Chen, Pi‐Tai Chou, U‐Ser Jeng, Yen‐Ju Cheng   +18 more
wiley   +1 more source