Results 101 to 110 of about 255,935 (312)
Effects of benralizumab on airway eosinophils in asthma with sputum eosinophilia
Background Many subjects with asthma exhibit sputum eosinophilia associated with exacerbations. Benralizumab targets eosinophils by binding interleukin-5 receptor alpha, inducing apoptosis via antibody-dependent cell-mediated cytotoxicity.
M. Laviolette +11 more
semanticscholar +1 more source
No Abstract.
openaire +2 more sources
Area of origin analysis for expirated patterns using HemoVision
Abstract Although bloodstain pattern analysis (BPA) can be performed on various types of patterns, there is a lack of research looking into whether the area of origin (AO) can be determined for expirated patterns. Expirated patterns are formed when blood is pushed out of an opening in the body by the force of air, in some cases forming a pattern of ...
Lathursha Kalaranjan, Eugene Liscio
wiley +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
BackgroundMultidrug-resistant tuberculosis (MDR-TB) refers to tuberculosis that resists at least two primary drugs, namely isoniazid and rifampicin. To assess the management of MDR-TB, sputum culture conversion is performed. This study aimed to determine
Kumar Gudesh +5 more
doaj +1 more source
Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome
Cystic fibrosis (CF) lungs are filled with thick mucus that obstructs airways and facilitates chronic infections. Pseudomonas aeruginosa is a significant pathogen of this disease that produces a variety of toxic small molecules.
R. Quinn +8 more
semanticscholar +1 more source
We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...
Akshi Kumar +14 more
wiley +1 more source
Respiratory tract infections are major global health issues that require rapid and accurate diagnostic methods. Multiplex quantitative PCR (qPCR) is commonly used for pathogen detection in respiratory samples.
Keun Ju Kim +4 more
doaj +1 more source
Identification of blaOXA-23 gene in resistant Pseudomonas aeruginosa strains isolated from cows and humans in Basra province, Iraq [PDF]
Background and Aim: Pseudomonas aeruginosa is an infectious agent of great importance for animals and humans. It causes serious infections that show high resistance to antibiotics.
Alyaa Sabti Jasim +4 more
doaj +1 more source

