Results 91 to 100 of about 255,935 (312)

Decreased Sputum Type-2 Gene Expression in COPD Current Smokers

International Journal of COPD
Thomas Southworth,1,2 Andrew Higham,1 Augusta Beech,1,2 Jian Li,1 Sophie Wolosianka,2 Dave Singh1,2 1Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health ...
Southworth T, Higham A, Beech A, Li J, Wolosianka S, Singh D   +5 more
doaj  

Pediatric Cystic Fibrosis Sputum Can Be Chemically Dynamic, Anoxic, and Extremely Reduced Due to Hydrogen Sulfide Formation

mBio, 2015
Severe and persistent bacterial lung infections characterize cystic fibrosis (CF). While several studies have documented the microbial diversity within CF lung mucus, we know much less about the inorganic chemistry that constrains microbial metabolic ...
Elise S. Cowley, S. Kopf, Alejandro LaRiviere, W. Ziebis, D. Newman   +4 more
semanticscholar   +1 more source

Strategies for enhancing sensitivity in lateral flow assays

VIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed, Jacopo Giaretta, Syamak Farajikhah, Fariba Dehghani   +3 more
wiley   +1 more source

Pre-Analytical Factors Affecting Extracellular DNA in Saliva

Diagnostics
Salivary DNA is widely used for genetic analyses because of its easy collection. However, its extracellular fraction in particular, similar to the extracellular DNA (ecDNA) in plasma, could be a promising biomarker for oral or systemic diseases.
Ľubica Janovičová, Dominika Holániová, Barbora Vlková, Peter Celec   +3 more
doaj   +1 more source

Vegetating Lupus Vulgaris in a Child

JEADV Clinical Practice, EarlyView.
Viktor Pushkarenko, Yana‐Karina Zovdun, Olga Pushkarenko   +2 more
wiley   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Exploring PI3Kδ Molecular Pathways in Stable COPD and Following an Acute Exacerbation, Two Randomized Controlled Trials

International Journal of COPD, 2021
Malcolm Begg,1 J Nicole Hamblin,1 Emily Jarvis,2 Glyn Bradley,3 Stephen Mark,4 David Michalovich,5 Mark Lennon,6 Hannah E Wajdner,5 Augustin Amour,5 Robert Wilson,1 Ken Saunders,5 Rikako Tanaka,7 Saki Arai,7 Teresa Tang,8 Cedric Van Holsbeke,9 Jan De ...
Begg M, Hamblin JN, Jarvis E, Bradley G, Mark S, Michalovich D, Lennon M, Wajdner HE, Amour A, Wilson R, Saunders K, Tanaka R, Arai S, Tang T, Van Holsbeke C, De Backer J, Vos W, Titlestad IL, FitzGerald JM, Killian K, Bourbeau J, Poirier C, Maltais F, Cahn A, Hessel EM   +24 more
doaj  

Sputum neutrophils are associated with more severe asthma phenotypes using cluster analysis

Journal of Allergy and Clinical Immunology, 2013
Background Clinical cluster analysis from the Severe Asthma Research Program (SARP) identified five asthma subphenotypes that represent the severity spectrum of early onset allergic asthma, late onset severe asthma and severe asthma with COPD ...
W. Moore, A. Hastie, Xingnan Li, Huashi Li, W. Busse, N. Jarjour, S. Wenzel, S. Peters, D. Meyers, E. Bleecker   +9 more
semanticscholar   +1 more source

A Painful Purpuric Rash in a Febrile Smoker

JEADV Clinical Practice, EarlyView.
Eugerta Dilka, Ina Sotiri, Irda Rrugeja, Monika Fida   +3 more
wiley   +1 more source

Mycobacterium intracellulare M.i.198—A Promising Strain for Studying Pathogenesis of Nontuberculous Mycobacterial Pulmonary Disease (NTM‐PD)

Microbiology and Immunology, EarlyView.
ABSTRACT In this review, we introduce a promising strain for studying pathogenesis of nontuberculous mycobacterial pulmonary disease (NTM‐PD), Mycobacterium intracellulare M.i.198. M.i.198 was isolated from a patient with progressive Mycobacterium avium‐intracellulare complex pulmonary disease (MAC‐PD) in whom surgical operation was required to ...
Yoshitaka Tateishi, Ryoji Maekura, Yukiko Nishiuchi, Sohkichi Matsumoto   +3 more
wiley   +1 more source