Results 41 to 50 of about 158,509 (197)

Influence of Stress and Antibiotic Resistance on Cell-Length Distribution in Mycobacterium tuberculosis Clinical Isolates

open access: yesFrontiers in Microbiology, 2017
Mycobacterial cellular variations in growth and division increase heterogeneity in cell length, possibly contributing to cell-to-cell variation in host and antibiotic stress tolerance. This may be one of the factors influencing Mycobacterium tuberculosis
Srinivasan Vijay   +17 more
doaj   +1 more source

Large Language Models for Clinical Trial Protocol Assessments

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The purpose was to evaluate the utility of large language models (LLMs) for reviewing the statistical analysis plan (SAP) and pharmacokinetics–pharmacodynamics (PK–PD) components of clinical trial protocols. Clinical trial protocols and SAPs were obtained from clinicaltrials.gov for a testbed of 15 small‐molecule drugs, biologics, and global antibiotic
Euibeom Shin   +2 more
wiley   +1 more source

Acute dyspnoea in cancer patients: Prevalence of acute heart failure, resource use and diagnostic accuracy of natriuretic peptides

open access: yesEuropean Journal of Heart Failure, EarlyView.
Cancer patients presenting to the emergency department ED with dyspnoea. Among 2153 patients presenting to the ED with dyspnea, 473 (22.0%) had an active or past cancer. Acute heart failure (AHF) was the most common final diagnosis in both groups. Pneumonia and cancer‐related dyspnoea were more common in cancer patients.
Paolo Bima   +20 more
wiley   +1 more source

Pathogenetic Reasoning of Administration of Mucolytic Agents for Respiratory Diseases in Children

open access: yesZdorovʹe Rebenka, 2015
The paper presents the mechanisms of cough and bronchial obstruction in lesions of the respiratory tract of various origins. The effect of microbial biofilms on the course of diseases was considered particularly. The methods to restore bronchial drainage
Ye.I. Yulish
doaj   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

open access: yesIbrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo   +7 more
wiley   +1 more source

DIAGNOSTIC VALUE OF SPUTUM AND ENDOTRACHEAL ASPIRATE GRAM STAIN

open access: yesZdravniški Vestnik, 2002
Background. For decades the microscopic examination of sample Gram stain has been one of the basic diagnostic procedures in the microbiology laboratory. Still opinions about usefulness of sputum and endotracheal aspirate Gram stains in initial management
Viktorija Tomič, Jurij Šorli
doaj  

Characteristics of Bacterial Microflora Isolated from Sputum of Patients with Pneumonia Registered in Khabarovsk City and Khabarovsk Territory in the Initial Period of COVID-19 Pandemic in May–June, 2020

open access: yesПроблемы особо опасных инфекций, 2020
Objective: to study the bacterial microflora in the sputum of patients with pneumonia caused by SARSCoV-2 or other pathogens.Materials and methods. The bacterial microflora of sputum of 173 patients with pneumonia admitted to hospitals in Khabarovsk and ...
A. P. Bondarenko   +5 more
doaj   +1 more source

Surgical site infections and sepsis in gynecological surgery

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento   +13 more
wiley   +1 more source

Application of Artificial Intelligence in Clinical Microbiology: From Research to Practice

open access: yesiLABMED, EarlyView.
This paper reviews the application of AI in clinical microbiology practice at home and abroad, including rapid pathogen identification, accurate characterization of microbial resistance patterns, optimization of laboratory workflows, and public health interventions.
Ting Ding, Yi‐Wei Tang, Xiaoke Hao
wiley   +1 more source

Cross‐continental transmission and host adaptation of Mycobacterium tuberculosis in China unveiled by population history reconstruction and adaptive evolution signal detection

open access: yesiMetaOmics, EarlyView.
This study showed that four Mycobacterium tuberculosis complex (MTBC) sub‐lineages might be introduced into China 1000–400 years ago via Europe‐China dispersal routes, where they diversified into local clades, and later underwent population expansions that coincided with periods of climatic cooling and warfare.
Wei Wu   +16 more
wiley   +1 more source

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