Results 91 to 100 of about 2,356 (123)
Nephroprotective effect of spexin in dogs and cats
BMC Veterinary ResearchBackground Kidney disease is a common and clinically significant problem in dogs and cats, yet the underlying pathophysiological mechanisms remain incompletely understood.
Maciej Gogulski +8 more
doaj +1 more source
Identification of Spx regulators in S. suis.
, 2014 (A) Schematic representation of the spx locus in S. suis. The genes and the ORF number in S. suis SC84 genome are indicated. Arrows indicate the direction of transcription and do not represent the exact length. (B) Multiple sequence alignment of S.
Jinquan Li (112721) +8 more
core +1 more source
YjbH is a novel negative effector of the disulphide stress regulator,Spx, in Bacillus subtilis.
, 2007 In the soil bacterium Bacillus subtilis Spx is a key regulator that controls expression, positively or negatively, of several genes in response to certain oxidative stresses that lead to the formation of unwanted disulphide bonds.
von Wachenfeldt, Claes +8 more
core +1 more source
MedicinaBackground/Objectives: Spexin (SPX) is a bioactive peptide involved in the regulation of appetite, lipid metabolism, and glucose homeostasis. This systematic review and meta-analysis aimed to evaluate exercise-induced changes in SPX levels and their ...
İsa Aydemir +4 more
doaj +1 more source
A post-transcriptional event contributes to activation of Spx in response to cell wall stress.
, 2018 (A) The spx gene was placed under control of IPTG as the only source of spx for the cells. (B) WT cells were grown with a fixed concentration of inducer and treated or not with 2 μg ml-1 ampicillin, 200 μg ml-1 fosfomycin, or 1 μg ml-1 vancomycin.
John D. Helmann (599799) +1 more
core +1 more source
Scientific ReportsSpexin (SPX), a recently identified adipokine, shows potential in enhancing insulin sensitivity, offering promising implications for metabolic health.
Kayvan Khoramipour +7 more
doaj +1 more source
Emerging roles of spexin in cardiovascular homeostasis
Frontiers in Cardiovascular MedicineSpexin (SPX) is a highly conserved, proteolytically processed 14-amino acid peptide hormone derived from spexin precursor, originally identified through a bioinformatics-based prediction algorithm.
Shuyun Wang +5 more
doaj +1 more source
Effect of SPX on ICaL and AP in adult mouse cardiac myocytes.
, 2016 A, Representative traces of ICaL during a 200-ms voltage-clamp pulse from −40 to 0 mV before (black) and after (red) exposure to 300 μM SPX. B–C, current–voltage (I-V) relationships of Ipeak (■, B) and Iend of pulse (●, C) under control conditions (black)
Young Min Bae (2549317) +11 more
core +1 more source
Circulating spexin and adiponectin as early biomarkers of insulin resistance in pediatric obesity
BMC Endocrine DisordersBackground Insulin resistance (IR) is a central pathological feature of childhood obesity. Spexin (SPX), an emerging endogenous metabolic regulatory peptide, plays a key role in regulating energy metabolism.
Biyao Lian +5 more
doaj +1 more source
, 2013 (A) Representative images of CD11c staining (upper sections) and CD206 staining (lower sections) in intra-islet areas in pancreas sections from each group. Scale bar = 100 µm. (B−D) CD11c-positive areas (B), CD206-positive areas (C), and M1/M2 ratios (D)
Koro Gotoh (291522) +13 more
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