SpxA1 and SpxA2 function as a stoichiometry-dependent regulatory rheostat governing virulence gene expression in group A <i>Streptococcus</i>. [PDF]
mBioMorrison GA +8 more
europepmc +1 more source
Characterization of the <i>PHO1</i> Gene Family in <i>Vigna radiata</i> L. and Its Expression Analysis Under Phosphate-Deficient Stress. [PDF]
Genes (Basel)Jiang L +7 more
europepmc +1 more source
The emerging importance of the SPX domain-containing proteins in phosphate homeostasis [PDF]
New Phytologist, 2012 SummaryPlant growth and development are strongly influenced by the availability of nutrients in the soil solution. Among them, phosphorus (P) is one of the most essential and most limiting macro‐elements for plants. In the environment, plants are often confronted with P starvation as a result of extremely low concentrations of soluble inorganic ...
James Whelan, Zhiye Wang, Huixia Shou
exaly +6 more sources
Control of plant phosphate homeostasis by inositol pyrophosphates and the SPX domain [PDF]
Current Opinion in Biotechnology, 2018 Proteins containing a SPX domain are involved in phosphate (Pi) homeostasis, including Pi transport and adaptation to Pi deficiency. The SPX domain harbors a basic surface binding Pi at low affinity and inositol pyrophosphates (PP-InsPs) at high affinity.
Yves Poirier +2 more
exaly +6 more sources
Transcriptome-Wide Identification and Expression Profiling of SPX Domain-Containing Members in Responses to Phosphorus Deprivation of Pinus massoniana [PDF]
Forests, 2021 The SPX domain-encoding proteins are believed to play important roles in phosphorus (Pi) homeostasis and signal transduction in plants. However, the overall information and responses of SPXs to phosphorus deficiency in pines, remain undefined. In this study, we screened the transcriptome data of Pinus massoniana in response to phosphorus deprivation ...
Fuhua Fan, Guijie Ding
exaly +3 more sources
The SPX domain of the yeast low‐affinity phosphate transporter Pho90 regulates transport activity
EMBO Reports, 2009 Yeast has two phosphate‐uptake systems that complement each other: the high‐affinity transporters (Pho84 and Pho89) are active under phosphate starvation, whereas Pho87 and Pho90 are low‐affinity transporters that function when phosphate is abundant. Here, we report new regulatory functions of the amino‐terminal SPX domain of Pho87 and Pho90.
Florian Freimoser +2 more
exaly +8 more sources
Loss of two families of SPX domain-containing proteins required for vacuolar polyphosphate accumulation coincides with the transition to phosphate storage in green plants [PDF]
Molecular Plant, 2021 Phosphorus is an essential nutrient for plants. It is stored as inorganic phosphate (Pi) in the vacuoles of land plants but as inorganic polyphosphate (polyP) in chlorophyte algae. Although it is recognized that the SPX-Major Facilitator Superfamily (MFS) and VPE proteins are responsible for Pi influx and efflux, respectively, across the tonoplast in ...
Benoît Menand, Lei Xu
exaly +4 more sources
Exploring the Amino Acid Residue Requirements of the RNA Polymerase (RNAP) α Subunit C-Terminal Domain for Productive Interaction between Spx and RNAP of Bacillus subtilis. [PDF]
Journal of Bacteriology, 2017 ABSTRACT Bacillus subtilis Spx is a global transcriptional regulator that is conserved among Gram-positive bacteria, in which Spx is required for preventing oxidatively induced proteotoxicity. Upon stress induction, Spx engages RNA polymerase (RNAP) through interaction with the C-terminal domain of the ...
Cierra A, Birch +3 more
exaly +4 more sources
A SPX domain vacuolar transporter links phosphate sensing to homeostasis in Arabidopsis
Molecular Plant, 2022 Excess phosphate (Pi) is stored into the vacuole through Pi transporters so that cytoplasmic Pi levels remain stable in plant cells. We hypothesized that the vacuolar Pi transporters may harbor a Pi-sensing mechanism so that they are activated to deliver Pi into the vacuole only when cytosolic Pi reaches a threshold high level.
Mingda Luan, Aigen Fu, Fugeng Zhao
exaly +3 more sources