Results 181 to 190 of about 29,092 (237)
Mechanistic insight into radical <i>S</i>-adenosylmethionine enzymes in lipid modification.
Nat Prod RepBlue-Lahom T +3 more
europepmc +1 more source
Production of Squalene in Bacillus subtilis by Squalene Synthase Screening and Metabolic Engineering [PDF]
Journal of Agricultural and Food Chemistry, 2020 Squalene synthase (SQS) catalyzes the conversion of two farnesyl pyrophosphates to squalene, an important intermediate in between isoprene and valuable triterpenoids.
Zheng Guan, Hegar Pramastya, Wim J Quax
exaly +3 more sources
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International Journal of Toxicology, 2023
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1982, along with updated information regarding product types and concentrations of use, and confirmed that Squalane and Squalene are safe as cosmetic ingredients in the practices of use and concentration as described in this report.
Monice, Fiume +10 more
openaire +2 more sources
The Expert Panel for Cosmetic Ingredient Safety reviewed newly available studies since their original assessment in 1982, along with updated information regarding product types and concentrations of use, and confirmed that Squalane and Squalene are safe as cosmetic ingredients in the practices of use and concentration as described in this report.
Monice, Fiume +10 more
openaire +2 more sources
Molecular and Cellular Biochemistry, 1979
In the first part of the review the background to the discovery of the asymmetric synthesis of squalene from two molecules of farnesyl pyrophosphate and NADPH is described, then the stereochemistry of the overall reaction is summarized. The complexity of the biosynthesis of squalene by microsomal squalene synthetase demanded the existence of some ...
G, Popják, W S, Agnew
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In the first part of the review the background to the discovery of the asymmetric synthesis of squalene from two molecules of farnesyl pyrophosphate and NADPH is described, then the stereochemistry of the overall reaction is summarized. The complexity of the biosynthesis of squalene by microsomal squalene synthetase demanded the existence of some ...
G, Popják, W S, Agnew
openaire +2 more sources
An NMR and molecular mechanics study of squalene and squalene derivatives
Chemistry and Physics of Lipids, 1994Various squalene derivatives, including squalene, squalene 2,3-epoxide (monoepoxide, SQME), squalene 2,3;22,23-diepoxide (SQDE), 2-aza-2,3-dihydrosqualene (SQN) and 2-aza-2,3-dihydrosqualene N-oxide (SQNO), were studied in chloroform solutions using ID high-resolution 1H spectra and 13C longitudinal relaxation studies, 2D proton NOESY and COSY and 2D ...
Lionello Pogliani +3 more
openaire +3 more sources
Metabolic Engineering of Saccharomyces cerevisiae To Overproduce Squalene
Journal of Agricultural and Food Chemistry, 2020 Squalene has wide applications in the food and pharmaceutical industries. Engineering microbes to produce squalene is a promising alternative for traditional production approaches.
Bei Gao, Feng-Qing Wang, Yuhong Ren
exaly +2 more sources
Vaccination, squalene and anti-squalene antibodies: Facts or fiction?
European Journal of Internal Medicine, 2010Squalene, a hydrocarbon obtained for commercial purposes primarily from shark liver oil and other botanic sources, is increasingly used as an immunologic adjuvant in several vaccines, including seasonal and the novel influenza A (H1N1) 2009 pandemic flu vaccines.
Giuseppe, Lippi +2 more
openaire +2 more sources
Squalene in Petroleum Asphaltenes
Science, 1981Squalene, 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene, a new biological marker, has been detected in various petroleum asphaltenes and their pyrolysis products. Since squalene is the most common triterpenoid in nature and the biological precursor of the important tetra- and pentacyclic triterpane markers, its detection in asphaltene ...
N, Samman +4 more
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Journal of the American Chemical Society, 2002
Squalene synthase (SQase) catalyzes the condensation of two molecules of farnesyl diphosphate (FPP) to form presqualene diphosphate (PSPP) and the subsequent rearrangement and NADPH-dependent reduction of PSPP to squalene (SQ). These reactions are the first committed steps in cholesterol biosynthesis.
Brian S J, Blagg +3 more
openaire +2 more sources
Squalene synthase (SQase) catalyzes the condensation of two molecules of farnesyl diphosphate (FPP) to form presqualene diphosphate (PSPP) and the subsequent rearrangement and NADPH-dependent reduction of PSPP to squalene (SQ). These reactions are the first committed steps in cholesterol biosynthesis.
Brian S J, Blagg +3 more
openaire +2 more sources