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The effect of consecutive steps of refining on squalene content of vegetable oils
Journal of Food Science and Technology, 2010 The aim of this study is to evaluate the effect of refining steps on the squalene content of some vegetable oils. A comparison has been made between the crude oils and consecutive steps of refining process (neutralization, bleaching, deodorization ...
Cevdet Nergiz
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[9] Synthesis of labeled squalene and squalene 2,3-oxide
1969Publisher Summary Squalene 2,3-oxide is an intermediate in the enzymatic cyclization of squalene to lanosterol, and, in consequence, this aspect of steroid and terpenoid biogenesis has become the center of renewed interest. This chapter describes the improved methods for the chemical synthesis of labeled squalene and squalene 2,3-oxide.
R.G. Nadeau, R.P. Hanzlik
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Synthesis, 1970
Wittig reactions of the ylide (Ph3P+CH-)2CH2 (I) with aliphatic aldehydes and ketones are described. A soln. of I in THF prepd. from (Ph3P+CH2)2CH2.2Br- was treated with an equimolar amt. of geranylacetone to give a stereoisomeric mixt. of II (norsqualene), b0.001 172-4 Deg, in 25% yield. III, b1 114-17 Deg, was similarly prepd.
Schlosser, Manfred, Piskala, Alois
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Wittig reactions of the ylide (Ph3P+CH-)2CH2 (I) with aliphatic aldehydes and ketones are described. A soln. of I in THF prepd. from (Ph3P+CH2)2CH2.2Br- was treated with an equimolar amt. of geranylacetone to give a stereoisomeric mixt. of II (norsqualene), b0.001 172-4 Deg, in 25% yield. III, b1 114-17 Deg, was similarly prepd.
Schlosser, Manfred, Piskala, Alois
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Chemical & Engineering News Archive, 1997
Chemists at the University of Utah, Salt Lake City, have trapped a cationic intermediate in the biosynthesis of squalene, a key precursor of cholesterol. Their insights into the remarkable enzymatic reaction may offer important leads to the design of drugs that reduce cholesterol levels by blocking squalene biosynthesis.
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Chemists at the University of Utah, Salt Lake City, have trapped a cationic intermediate in the biosynthesis of squalene, a key precursor of cholesterol. Their insights into the remarkable enzymatic reaction may offer important leads to the design of drugs that reduce cholesterol levels by blocking squalene biosynthesis.
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Metabolic engineering of for improving squalene production
Bioresource Technology, 2021Yun Tian, Hu-Hu Liu, Xiao-Jun Ji
exaly
Presence of squalene in staphylococcus
Archives of Biochemistry and Biophysics, 1968G, Suzue +3 more
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The Crystal Structure of Squalene
Angewandte Chemie International Edition in English, 1976J, Ernst, W S, Sheldrick, J H, Fuhrhop
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