Scientific Reports, 2021 Extracellular vesicles (EVs) are mediators of the immune system response. Encapsulated in EVs, microRNAs can be transferred between cancer and immune cells.
Elisangela de Paula Silva +13 more
doaj +1 more source
Gene Co-expression Network analysis of Lung Squamous Cell Carcinoma data [PDF]
arXiv, 2018 We performed a gene co-expression analysis on Lung Squamous Cell Carcinoma data to find modules (groups) of genes that may highly impact the growth of these type of tumors. Additionally, we used cancer survival data to relate modules to prognostic significance in terms of survival time. Analysis on RNA-seq data revealed modules which are significant in
arxiv
Rank the triplets: A ranking-based multiple instance learning framework for detecting HPV infection in head and neck cancers using routine H&E images [PDF]
arXiv, 2022 The aetiology of head and neck squamous cell carcinoma (HNSCC) involves multiple carcinogens such as alcohol, tobacco and infection with human papillomavirus (HPV). As the HPV infection influences the prognosis, treatment and survival of patients with HNSCC, it is important to determine the HPV status of these tumours. In this paper, we propose a novel
arxiv
Does Notch play a tumor suppressor role across diverse squamous cell carcinomas? [PDF]
, 2016 The role of Notch pathway in tumorigenesis is highly variable. It can be tumor suppressive or pro-oncogenic, typically depending on the cellular context.
Biswas, Sangita +5 more
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
An Amalgamation of Classical and Quantum Machine Learning For the Classification of Adenocarcinoma and Squamous Cell Carcinoma Patients [PDF]
arXiv, 2018 The ability to accurately classify disease subtypes is of vital importance, especially in oncology where this capability could have a life saving impact. Here we report a classification between two subtypes of non-small cell lung cancer, namely Adeno- carcinoma vs Squamous cell carcinoma. The data consists of approximately 20,000 gene expression values
arxiv
A digital score of tumour-associated stroma infiltrating lymphocytes predicts survival in head and neck squamous cell carcinoma [PDF]
arXiv, 2021 The infiltration of T-lymphocytes in the stroma and tumour is an indication of an effective immune response against the tumour, resulting in better survival. In this study, our aim is to explore the prognostic significance of tumour-associated stroma infiltrating lymphocytes (TASILs) in head and neck squamous cell carcinoma (HNSCC) through an AI based ...
arxiv
Warty carcinoma of uterine cervix - review of the literature and case report [PDF]
, 2020 Introduction. The Histological Classification of Epithelial Tumors of the Uterine Cervix of the World Health Organization includes inter alia warty carcinoma as a variant of squamous cell carcinoma.
Balalau, Oana Denisa +3 more
core +1 more source
Pattern of Recurrence after Curative Resection of Local (Stage I and II) Non-Small Cell Lung Cancer: Difference According to the Histologic Type [PDF]
, 2004 The aim of the present study was to evaluate the pattern of recurrence after complete resection of pathological stage I, II non-small cell lung cancer, especially according to the cell type.
Cagini +13 more
core +2 more sources
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source