Results 61 to 70 of about 201,440 (215)

Easily detected signs of perineural tumour spread in head and neck cancer

open access: yesInsights into Imaging, 2018
Perineural tumour spread (PNTS) in head and neck oncology is most often caused by squamous cell carcinoma. The most frequently affected nerves are the trigeminal and facial nerves. Up to 40% of patients with PNTS may be asymptomatic. Therefore, the index
Jan Willem Dankbaar   +3 more
doaj   +1 more source

The molecular pathogenesis of head and neck squamous cell carcinoma [PDF]

open access: yesJournal of Clinical Investigation, 2012
Squamous cell carcinoma of the head and neck (HNSCC) is a relatively common human cancer characterized by high morbidity, high mortality, and few therapeutic options outside of surgery, standard cytotoxic chemotherapy, and radiation. Although the most important risk factors are tobacco use and alcohol consumption, the disease is also linked to ...
S Michael, Rothenberg, Leif W, Ellisen
openaire   +2 more sources

SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. [PDF]

open access: yes, 2019
BACKGROUND:Programmed cell death ligand-1 (PD-L1) expression on tumor cells (TCs) is associated with improved survival in patients with head and neck squamous cell carcinoma (HNSCC) treated with immunotherapy, although its role as a prognostic factor is ...
Baste, Neus   +19 more
core   +1 more source

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas [PDF]

open access: yes, 2018
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with ...
Abdel-Rahman, Mohamed H.   +784 more
core   +2 more sources

Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis [PDF]

open access: yes, 2016
Human papillomavirus induced (HPV+) cancer incidence is rapidly rising, comprising 60–80% of oropharyngeal squamous cell carcinomas (OPSCCs); while rare, recurrent/metastatic disease accounts for nearly all related deaths.
Coppock, Joseph D   +8 more
core   +2 more sources

ASSESSMENT OF BLOOD SERUM PROTEOME IN PATIENTS WITH SQUAMOUS CELL HEAD AND NECK CARCINOMA

open access: yesСибирский онкологический журнал, 2016
We compared the serum proteome profiles of squamous cell head and neck carcinoma patients with metastases, without metastases and healthy volunteers using the combination of gradient gel-electrophoresis (1D-SDS PAGE) and mass-spectrometry.
G. V. Kakurina   +4 more
doaj  

Quantitative proteomics identifies biomarkers to distinguish pulmonary from head and neck squamous cell carcinomas by immunohistochemistry

open access: yesThe Journal of Pathology: Clinical Research, 2022
The differentiation between a pulmonary metastasis and a newly developed squamous cell carcinoma of the lung in patients with prior head and neck squamous cell carcinoma (HNSCC) is difficult due to a lack of biomarkers but is crucially important for the ...
Annika Richter   +12 more
doaj   +1 more source

Predictive Potential of Head and Neck Squamous Cell Carcinoma Organoids [PDF]

open access: yesCancer Discovery, 2019
Abstract Summary: In this issue of Cancer Discovery, Driehuis and colleagues establish culture conditions for the rapid, efficient, and long-term expansion of healthy human oral mucosa and head and neck squamous cell carcinoma (HNSCC) tumor organoids.
Sarah J, Hill, Alan D, D'Andrea
openaire   +2 more sources

Replication-Competent Herpes Simplex Virus Vector G207 and Cisplatin Combination Therapy for Head and Neck Squamous Cell Carcinoma

open access: yesNeoplasia: An International Journal for Oncology Research, 1999
Replication-competent virus vectors are attractive therapeutic agents for cancer. G207, a second-generation, multimutated herpes simplex virus type 1 (HSV-1), is one such vector that is safe in primates and efficacious against human tumors in athymic ...
Ali Chahlavi   +3 more
doaj   +1 more source

Measuring the response of human head and neck squamous cell carcinoma to irradiation in a microfluidic model allowing customized therapy [PDF]

open access: yes, 2017
Radiotherapy is the standard treatment for head and neck squamous cell carcinoma (HNSCC), however, radioresistance remains a major clinical problem despite significant improvements in treatment protocols. Therapeutic outcome could potentially be improved
Beavis, Andrew W.   +5 more
core   +1 more source

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