Results 51 to 60 of about 878,007 (304)

Challenges in using cultured primary rodent hepatocytes or cell lines to study hepatic HDL receptor SR-BI regulation by its cytoplasmic adaptor PDZK1. [PDF]

PLoS ONE, 2013
PDZK1 is a four PDZ-domain containing cytoplasmic protein that binds to a variety of membrane proteins via their C-termini and can influence the abundance, localization and/or function of its target proteins.
Kosuke Tsukamoto, Lorenna Buck, Walker Inman, Linda Griffith, Olivier Kocher, Monty Krieger   +5 more
doaj   +1 more source

Ultra‐Fast Non‐Volatile Resistive Switching Devices with Over 512 Distinct and Stable Levels for Memory and Neuromorphic Computing

Advanced Functional Materials, EarlyView.
A materials and device design concept that comprises a self‐assembled ultra‐thin epitaxial ion‐transporting layer, an amorphous oxide overcoat oxygen‐blocking layer, and a partial filament formed during an electroforming step is proposed for low‐current multilevel resistive switching devices.
Ming Xiao, Markus Hellenbrand, Nives Strkalj, Babak Bakhit, Zhuotong Sun, Nikolaos Barmpatsalos, Dovydas Joksas, Hongyi Dou, Zedong Hu, Ping Lu, Samip Karki, Sundar Kunwar, Jonathan D. Major, Aiping Chen, Haiyan Wang, Quanxi Jia, Adnan Mehonic, Judith L. MacManus‐Driscoll   +17 more
wiley   +1 more source

The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence

Reproductive Biology and Endocrinology, 2015
BackgroundHuman prostate cancer represents one of the most frequently diagnosed cancers in men worldwide. Currently, diagnostic methods are insufficient to identify patients at risk for aggressive prostate cancer, which is essential for early treatment ...
David Schörghofer, K. Kinslechner, A. Preitschopf, Birgit Schütz, C. Röhrl, M. Hengstschläger, H. Stangl, M. Mikula   +7 more
semanticscholar   +1 more source

The HDL receptor SR-BI: a new therapeutic target for atherosclerosis?

Molecular Medicine Today, 1999
Although high-density lipoprotein (HDL) metabolism is a crucial process for cholesterol homeostasis and coronary heart disease, therapeutic approaches for selective modification of plasma HDL levels are not currently available. The discovery of well-defined cell-surface HDL receptors should provide new avenues for treatment of atherosclerotic ...
Acton, SL, Kozarsky, KF, Rigotti, A
openaire   +7 more sources

Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine

Advanced Functional Materials, EarlyView.
Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang, Xin Zhang, Denghui Xie, Chunying Chen, Zhifeng Huang, Zhong Alan Li   +5 more
wiley   +1 more source

Making Photoresponsive Metal–Organic Frameworks an Effective Class of Heterogeneous Photocatalyst

Advanced Functional Materials, EarlyView.
This review summarizes photoresponsive MOFs for photocatalytic applications, focusing on their capacity to enhance light harvesting, charge transfer, and surface reactions. While existing studies provide foundational insights, emerging characterization techniques enable a deeper understanding of photoresponsive MOFs.
Rui Liu, Hao Wu, Hoi Ying Chung, Yun Hau Ng   +3 more
wiley   +1 more source

Near‐Infrared Circularly Polarized Electroluminescence with Switchable Handedness in Organic LEDs

Advanced Functional Materials, EarlyView.
The first fully‐organic circularly polarized near‐infrared OLED, using a co‐assembled active layer of ITIC and a chiral inducer, exhibits dissymmetry values up to 0.074 and 1.65 Wsr−1m−2 radiance. The circular polarization sign can be switched by manipulating the position of the recombination zone, resulting in enhanced device performance and stability.
Francesco Zinna, Chiara Botta, Silvia Luzzati, Lorenzo Di Bari, Umberto Giovanella   +4 more
wiley   +1 more source

C323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake[S]

Journal of Lipid Research, 2011
Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake.
Ling Guo, Min Chen, Zhiqing Song, Alan Daugherty, Xiang-An Li   +4 more
doaj  

Quantitative analysis of SR-BI-dependent HDL retroendocytosis in hepatocytes and fibroblasts [PDF]

Journal of Lipid Research, 2006
Previous studies have suggested that HDL retroendocytosis may play a role in scavenger receptor class B type I (SR-BI)-dependent selective lipid uptake in a cell-specific manner. To investigate this possibility, we developed methods to quantitatively measure HDL uptake and resecretion in fibroblast (COS-7) and hepatocyte (HepG2) cells expressing ...
Shoba Shetty, Nancy R. Webb, Erik Eckhardt, Bing Sun, Deneys R. van der Westhuyzen   +4 more
openaire   +4 more sources

Supercompliant Lattice Boosts n‐type AgSbTe2 Thermoelectrics

Advanced Functional Materials, EarlyView.
The supercompliant lattice design enables the first realization of n‐type electrical transport in AgSbTe2 by overcoming intrinsic electron‐killer defects and exceeding the doping limits imposed by the conventional Hume–Rothery rule. Accordingly, the best performance n‐type Ag0.8Na0.3Sb0.6Bi0.4Te2 sample achieves a low κ of 0.27 W·m−1·K−1 that ...
Ruoyan Li, Shuai Han, Chunyu Zhang, Suyao Liu, Wen Yin, Yuanguang Xia, Pengfei Liu, Zhen‐Hua Ge, Dongyao Zhao, Bingchao Yang, Lulu Huang, Zhi Zhang, Yongsheng Zhang, Yuan Yu, Bangzhi Ge, Chongjian Zhou   +15 more
wiley   +1 more source