Results 271 to 280 of about 242,192 (301)

Targeting SRC kinase (SRC) in melanoma cells.

Journal of Clinical Oncology, 2010
8584 Background: The SRC family of tyrosine kinases have been implicated in melanoma progression.
A. J. Eustace, T. Mahgoub, S. Kennedy, J. Crown, A. Larkin, D. Tryfonopoulos, L. O'Driscoll, M. Clynes, N. O'Donovan   +8 more
openaire   +1 more source

A target for Src in mitosis

Nature, 1994
The activity of the c-Src protein is increased during cell-cycle stage G1 in fibroblasts stimulated with certain growth factors, and at the G2/M transition, but little is known about Src substrates in these circumstances. In contrast, cells transformed with activated Src contain many tyrosine-phosphorylated proteins.
S, Fumagalli, N F, Totty, J J, Hsuan, S A, Courtneidge   +3 more
openaire   +2 more sources

Src activation in melanoma and Src inhibitors as therapeutic agents in melanoma

Melanoma Research, 2009
Src signaling has been implicated in several malignancies including melanoma. The prevalence of Src activation in human melanoma and the effect of the newer Src inhibitors, dasatinib, and bosutinib (SKI-606), as single agents or in combination, on melanoma cell lines is not well established.
Jade, Homsi, Christopher L, Cubitt, Shumin, Zhang, Pamela N, Munster, Hua, Yu, Daniel M, Sullivan, Richard, Jove, Jane L, Messina, Adil I, Daud   +8 more
openaire   +2 more sources

Expression of c-Src and phospho-Src in epithelial ovarian carcinoma

Molecular and Cellular Biochemistry, 2013
Abnormal c-Src expression and activation has been observed in a number of tumors. To determine the therapeutic potential of Src inhibitors for ovarian cancer patients, this study aimed to explore the expression patterns of c-Src and phospho-Src in epithelial ovarian cancer.
Yong-Wen, Huang, Chen, Chen, Man-Man, Xu, Jun-Dong, Li, Juan, Xiao, Xiao-Feng, Zhu   +5 more
openaire   +2 more sources

SRC

2012
  +4 more sources

Src

2014
  +4 more sources

Src

2006
openaire   +2 more sources

Role of Src expression and activation in human cancer

Oncogene, 2000
Rosalyn B Irby, Yeatman Timothy J
exaly  

Targeted Degradation of Transcription Coactivator SRC‐1 through the N‐Degron Pathway

Angewandte Chemie - International Edition, 2020
Yeongju Lee, Do Hoon Kwon, Min Hyeon Shin   +2 more
exaly  

Selected glimpses into the activation and function of Src kinase

Oncogene, 2000
Donald J Fujita, Fujita Donald J
exaly