Results 151 to 160 of about 96,025 (288)

Mystery and misery of locally‐delivered drug therapy in periodontics. Historical concepts and current state

open access: yesPeriodontology 2000, EarlyView.
Abstract The primary objective is to critically analyze approaches to local therapy for periodontal disease, particularly in light of its well‐established systemic implications. We specifically address common misconceptions and overestimations regarding the potential of local treatments in contrast to their actual clinical effectiveness.
Andrea Mombelli, Alkisti Zekeridou
wiley   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni   +7 more
wiley   +1 more source

The European contribution to osseous resective surgery for the treatment of residual pockets and furcation defects

open access: yesPeriodontology 2000, EarlyView.
Abstract For decades, osseous resective surgery along with apically positioned flap procedure has been advocated as a predictable treatment option to reduce residual pockets and minimize periodontal complications during supportive periodontal care. More recently, Fiber Retention Osseous Resective Surgery (FibReORS) has been suggested to reduce the ...
Gianfranco Carnevale   +3 more
wiley   +1 more source

The efficacy of biologic factors on the surgical therapy of periodontal suprabony defects: A systematic review and network meta‐analysis of randomized clinical trials

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives This systematic review investigated the efficacy of biologic factors in the surgical treatment of periodontal suprabony defects. Materials and Methods Three databases were searched to identify RCTs comparing open‐flap debridement (OFD) combined with biologic factors only, or combined with bone substitute, and/or barriers to the same
Carrie Chew   +5 more
wiley   +1 more source

Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin   +6 more
wiley   +1 more source

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh   +7 more
wiley   +1 more source

Impact and efficacy of systemic antibiotics for peri‐implant diseases treatment: A systematic review and meta‐analysis on clinical and microbiological outcomes

open access: yesPeriodontology 2000, EarlyView.
Abstract Aim To evaluate the adjunctive effects of systemic antibiotics (SA) on clinical and microbiological outcomes in the treatment of peri‐implant diseases. Materials and Methods A systematic review and meta‐analysis were conducted following PRISMA guidelines and registered on PROSPERO (CRD420251059056).
Gaetano Isola   +5 more
wiley   +1 more source

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